Found 8 Glioblastoma multiforme trials
A listing of Glioblastoma multiforme medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study investigates therapies for glioblastoma, a type of brain cancer. The purpose of this study is to evaluate multiple therapies for newly diagnosed and recurrent glioblastoma using a response adaptive randomization platform. This method assigns participants to different study arms based on their performance, aiming to identify effective treatments …
This study investigates the safety and feasibility of a treatment involving specialized T cells, known as CART-EGFR-IL13Ra2 cells, for patients with recurrent glioblastoma. The study focuses on patients whose tumors have a specific genetic feature called EGFR amplification.Participants in this study will receive an infusion of their own T cells …
This study investigates the safety of using a type of immune cell therapy in patients with glioblastoma. The study will use T cells, which are a type of white blood cell, that have been modified to target specific proteins on cancer cells. These proteins are known as EGFR and IL13Ra2. …
This study investigates the effectiveness of personalized mapping techniques for patients with Glioblastoma, a type of brain cancer. The purpose of this study is to compare two different mapping methods used in tumor treating fields (TTFields) therapy, which is a type of electrical therapy that has shown to improve survival …
Glioblastoma (GBM) is the most common primary brain tumor in adults and is uniformly fatal. During standard adjuvant treatment for GBM following initial surgical resection of the tumor, patients are treated with a combination of radiation and chemotherapy. During and after this adjuvant treatment, patients are monitored for disease progression …
The main focus of the project will be using advanced imaging techniques on both 3T and 7T MRI systems for the creation of treatment planning maps. This project focuses on incorporating readily available 3T & 7T imaging and using computer based algorithms to develop a cumulative approach to devising a …
This study investigates the use of investigational cells called CART-EGFR-IL13Ra2 in patients with recurrent glioblastoma, a type of brain cancer. The study aims to evaluate the safety and effectiveness of these cells in patients whose cancer has returned after previous treatment.Participants will receive CART-EGFR-IL13Ra2 cells along with chemotherapy or before …
Primary Objectives:To perform metabolic phenotyping of treatment naïve and recurrent GBM by multitracer [18F]Fluciclovine and 18F-FDG PET. Secondary Objectives:To compare uptake measures of 18F-Fluciclovine and 18F-FDG and MRI quantification of glutamate and lactate levels to tumor tissue laboratory assays (RNA seq and proteomics) of glutamine/glutamate, glucose, and lactate metabolism. To …
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