Found 11 Esophageal Disorders trials
A listing of Esophageal Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study investigates solid tumors. Participants will provide clinical data and biological samples to support cancer biomarker research.The focus of this study is to evaluate the development of tests for cancer detection and assessing the risk of cancer recurrence.Who can participate: Adults aged 18 and older with a confirmed diagnosis …
To establish novel cell lines from patients with and without Barretts with GERD so we can provide data to support grant proposals to be submitted for NIH funding. N/A N/A
This study investigates the best way to treat patients with Barrett's esophagus and low-grade dysplasia by comparing two procedures: endoscopic surveillance and endoscopic eradication therapy. Low-grade dysplasia is an early form of abnormal cell growth that may not always progress to cancer. Endoscopic surveillance involves using a camera-equipped tube to …
This study investigates the safety and effectiveness of an investigational oral medication designed to degrade SMARCA2 in patients with advanced or metastatic solid tumors that have a SMARCA4 mutation. The purpose of this study is to understand how the investigational medication affects the body, how it is processed by the …
This study investigates the combination of an investigational medication, administered as telomelysin (OBP-301), with pembrolizumab in patients with advanced or metastatic gastric or gastroesophageal junction cancer. The purpose of this study is to determine if this combination is safe and effective for patients whose cancer has progressed despite previous treatments.Participants …
This study investigates the safety and effectiveness of adding RP2, an investigational treatment, to the standard chemotherapy regimen, FLOT, for patients with stage II or higher, non-metastatic gastroesophageal adenocarcinoma. The purpose of this study is to determine if injecting RP2 directly into the tumors of the stomach and esophagus, combined …
The purpose of this study is to investigate whether adding investigational medications to standard chemotherapy is effective for treating resectable HER2+ esophagogastric cancer. In this study, patients will receive investigational medications in combination with chemotherapy before surgery to see if this approach can improve treatment outcomes.Participants in this study will …
This study investigates the use of FAPI-74 PET/CT in adults with gastric or esophageal cancer. The purpose is to explore the diagnostic performance of this imaging technique.The study focuses on evaluating how well FAPI-74 PET/CT detects metastatic disease in these conditions. It assesses the effectiveness and accuracy of this imaging …
This study investigates the use of an investigational medication in patients with advanced solid tumors, specifically focusing on its effects as a single agent or in combination with other therapies. The purpose is to determine the recommended Phase II dose and to evaluate its safety, tolerability, and anti-tumor activity. The …
This study investigates the safety and effects of an investigational radioligand therapy in adults with advanced or metastatic solid tumors that have high levels of fibroblast activation protein (FAP). The study aims to understand how the investigational therapy interacts with FAP. The purpose of this study is to evaluate the …
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