Found 9 Epilepsy trials
A listing of Epilepsy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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Primary Objective: To compare the efficacy of 2 doses of BHV-7000 to placebo as an adjunctive therapy for refractory focal onset epilepsy as measured by the change from baseline in 28-day average seizure frequency. Secondary Objcetives: -To compare the efficacy of 2 doses of BHV-7000 to placebo as adjunctive therapy …
This research study is being conducted to learn how well Staccato Alprazolam works and how safe it is for the treatment of epilepsy. Some participants will receive a placebo.
The current study presents a unique opportunity to measure the immediate neural responses to brief, non-therapeutic transcranial low-intensity focused ultrasound (LIFU) pulses using intracranial electrodes. By recording time-locked signals in local and distant brain regions we can characterize circuit connectivity in real-time. We will use adult patients undergoing intracranial electrophysiological …
TRACK-TBI EPI is an observational study of the TRACK-TBI longitudinal cohort. Subjects will be contacted 2-5 years after their index TBI for consent to a phone interview. Those who screen positive for possible post-traumatic epilepsy will be invited for an in person visit, which will involve a clinical evaluation by …
Open label extension of RISE, a study of BHV7000 in patients 18+ with focal epilepsy.
The purpose of this research study is to learn more about how the brain stores and retrieves different kinds of information from memory, and whether brain stimulation can improve the storage and retrieval of memories. We are enrolling subjects with drug-resistant epilepsy, who are expected to undergo placement of electrodes …
The objective is to obtain cortical tissue that is clinically suspected to be normal brain tissue from patients undergoing epilepsy surgical resection, tumor resection, and normal pressure hydrocephalus (NPH) requiring placement of a shunt catheter. electrophysiological assays generating tissue cultures
We are conducting research studies on how immune system cells contribute to inflammatory conditions of the nervous system, such as multiple sclerosis, neuromyelitis optica (NMO), encephalitis, head injury, epilepsy, Parkinson's disease (PD), Alzheimer's disease (AzD), Lou Gherig's disease (amyotrophic lateral sclerosis; ALS) frontotemporal dementia (FTD) and others. This includes investigating …
The overall study objectives include evaluating the long-term safety and tolerability of Staccato alprazolam in patients with stereotypical prolonged epilepsy. The study will evaluate the probability of success of repeated treatment with Staccato alprazolam and of repeated treatment with Staccato alprazolam with no recurrence of seizure(s) up to 2 hours …
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