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Found 27 Diabetes Mellitus, Type 2 trials

A listing of Diabetes Mellitus, Type 2 medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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MRI of GLP1 Agonist Effects
20 years - 100 years
All genders
This study looks at the effects of GLP-1 receptor agonist (GLP1-RA) medications such as Zepbound, Wegovy, etc. on muscle health in adults with obesity. This will be evaluated using an MRI scan before starting a GLP-1 RA  and after losing 10% of body weight on the GLP-1 RA.
The GRoceries Aimed at Increasing Nutrition Study (GRAIN Study)
45 years - 70 years
All genders
We are looking for adults ages 45-70 to take part in an 18-week study about people‘s online grocery shopping habits. You’ll get a free Walmart+ membership for your grocery deliveries and receive $10 back on all weekly orders over $35. You may earn over $200 in total for completing study …
UPCC 31920 Penn Medicine BioBank
18 years - 100 years
All genders
Observational
The Penn Medicine Biobank is collecting and storing biological specimens such as blood, as well as health information from volunteers. These samples and this information allow researchers to use them for research studies including but not limited to COVID-19, cancer, diabetes, and heart disease. 
99 years or below
Female
The goal is to collect real-world data on strategies being employed by pregnant individuals with T1D in the U.S. to manage their disease and to assess glycemic and pregnancy outcomes associated with these strategies. This is an observational study, with participant-data collection supported by clinical sites and the coordinating center, …
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Online study
18 years - 79 years
All genders
The purpose of this study is to (1) determine if circulating metabolites, including sphingolipids, are associated with severity of diabetic retinopathy (DR) in participants with diabetes mellitus type 2 and to (2) identify metabolic risk and protective factors that are associated with the development and progression of DR.
Effect of GLP-1 Agonist Therapy on Insulin Secretion in Adults with Pancreatic Insufficient Cystic Fibrosis and Abnormal Glucose Tolerance: a randomized  open-label  cross-over trial
18 years - 50 years
All genders
The research study is being conducted to better understand Cystic-Fibrosis Related Diabetes (CFRD) and to see the effects of an analog of the gut incretin hormone, GLP-1 (dulaglutide), has on individuals like with abnormal glucose tolerance. GLP-1 (dulaglutide) helps the pancreas release insulin, which controls blood sugar levels from getting …
Noninvasive Quantification of Renal Oxygen Utilization in Early Kidney Disease
18 years - 59 years
Accepts healthy volunteer
All genders
Type 2 diabetes is the most common cause of chronic kidney disease (CKD). In people with diabetes, the kidneys do not function normally and continuously require more oxygen to remove waste from the body. This process, in-turn, depletes the available supply of oxygen, causes damage to the tissue itself, and …
TZIELD® (teplizumab-mzwv) in Patients with Stage 2 Type 1 Diabetes
8 years or above
All genders
Are you at risk for type 1 diabetes?Are you willing to receive a phone call every 6 months?For patients treated with TZIELD AND NOT treated with TZIELDYou may qualify to participate in an observational research studyAn observational study (you will not receive any experimental medication)Does not require on-site visitsParticipation will …
Cadisegliatin as Adjunctive Therapy in Type 1 Diabetes: A 26-Week Double-Blind, Randomized, Placebo-Controlled Phase 3 Study
18 years or above
All genders
Phase 3
The purpose of this study is to learn about and compare the effects of cadisegliatin (also called “TTP399”) compared to placebo to find out which is better for reducing the episodes of low blood sugar (hypoglycemia) related to type 1 diabetes, lowering HbA1c, and to see how safe cadisegliatin is …
A Phase 1/2 Study to Evaluate the Safety, Tolerability, and Efficacy of VX-880 in Subjects Who Have Type 1 Diabetes Mellitus with Impaired Hypoglycemic Awareness and Severe Hypoglycemia
18 years - 65 years
All genders
Phase 1/2
Interventional
In T1D the body’s immune system destroys insulin producing cells called beta cells. This meansthe body cannot produce enough insulin to control the amount of sugar in the blood. Beta cellsare located in the pancreas and are part of clusters of cells called pancreatic islets.These cells produce hormones such as …
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