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Found 216 Diabetes Mellitus, Type 2 trials

A listing of Diabetes Mellitus, Type 2 medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 HeartShare

HeartShare

30-99 years
Healthy Volunteer
All genders
The overall goal of the HeartShare Deep Phenotyping Study is to create a rich repository of data (e.g., demographic, social determinants of health, clinical, physiological, laboratory), images, and multi-omics (blood and tissue samples) that will serve as a resource for investigators to identify novel HFpEF subtypes and mechanisms (biological and …
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Online study
 Evaluating the Safety and Efficacy of Tradipitant vs. Placebo in Idiopathic and Diabetic Gastroparesis

Evaluating the Safety and Efficacy of Tradipitant vs. Placebo in Idiopathic and Diabetic Gastroparesis

18-70 years
All genders
Phase 3
Interventional
To investigate the safety and efficacy of Tradipitant versus placebo in relieving nausea and other symptoms of gastroparesis.
 Early Diagnosis of TTR Amyloid

Early Diagnosis of TTR Amyloid

40-75 years
All genders
Interventional
The purpose of this study is to find out if we can detect a disease of the heart called cardiac transthyretin (TTR) amyloidosis early. People develop cardiac TTR amyloidosis due to an accumulation of a transthyretin protein in the heart. This can happen as part of an aging process (wild …
 Direct Lysis of Staph Aureus Resistant Pathogen Trial of Exebacase (DISRUPT)

Direct Lysis of Staph Aureus Resistant Pathogen Trial of Exebacase (DISRUPT)

12-99 years
All genders
Phase 3
Interventional
The purpose of this superiority study is to evaluate the efficacy and safety of exebacase in addition to standard of care antibiotics (SoCA) compared with SoCA alone for the treatment of patients with Staphylococcus aureus (S. aureus) bloodstream infections (BSI), including right-sided infective endocarditis (IE). Patients will be randomized to …
 Study to Evaluate the Safety and Efficacy of GS-5423 and GS-2872 in Combination With Lenacapavir (GS-6207) in Virologically Suppressed Adults With HIV-1 Infection

Study to Evaluate the Safety and Efficacy of GS-5423 and GS-2872 in Combination With Lenacapavir (GS-6207) in Virologically Suppressed Adults With HIV-1 Infection

18-65 years
All genders
Phase 1
Interventional
The primary objective of this study is to evaluate the safety and tolerability of a combination of the broadly neutralizing antibodies (bNAbs) GS-5423 and GS-2872 in combination with the HIV capsid inhibitor lenacapavir (LEN).
 Personalized Atrial Fibrillation Ablation with Ablation Index Adapted to Left Atrial Wall Thickness: The Ablate-by-LAW Pilot Study

Personalized Atrial Fibrillation Ablation with Ablation Index Adapted to Left Atrial Wall Thickness: The Ablate-by-LAW Pilot Study

18-99 years
All genders
Interventional
This study will use ADAS 3D LA™ software modules on your cardiac computed tomography angiography (CTA) to analyze Left Atrial Wall Thickness (LAWT) and the distance from the LA to the Esophagus (LA DIST). A CTA is a noninvasive test used to focus on coronary arteries. It allows doctors to …

A phase 3 multicenter randomized double-blind placebo-controlled study to assess the efficacy and safety of 400 mg twice a day oral ladarixin in patients with new-onset type 1 diabetes and a low residual -cell function

99 years and younger
All genders
The objective of this clinical trial is to assess whether ladarixin treatment is effective in preserving -cell function and delaying the progression of T1D in adolescent and adult patients. The safety of ladarixin in the specific clinical setting will be also evaluated.
 RevitaT2Di Pivotal Study (REVITALIZE 1)

RevitaT2Di Pivotal Study (REVITALIZE 1)

21-70 years
All genders
The Revitalize-1 Study will look at a potential procedure called duodenal mucosal resurfacing (DMR). The DMR procedure acts on the first layer (mucosa) of the duodenum (the part of the small intestine located immediately after the stomach). By removing an excess layer, the treatment may improve blood sugar control. This …
 Research Study on Whether Semaglutide Works in People With Non-alcoholic Steatohepatitis (NASH)

Research Study on Whether Semaglutide Works in People With Non-alcoholic Steatohepatitis (NASH)

18-99 years
All genders
Phase 3
Semaglutide is a medicine studied in patients with NASH. Semaglutide is a well-known medicine, which is already used by doctors to treat type 2 diabetes in many countries. Participants will need to inject themselves with medicine under the skin. Participants will need to do this once a week. The study …
 Research Study on Whether a Combination of 2 Medicines  Works in People With Non-alcoholic Steatohepatitis (NASH)

Research Study on Whether a Combination of 2 Medicines Works in People With Non-alcoholic Steatohepatitis (NASH)

18-99 years
All genders
This study is being done to see if a combination of 2 medicines (called NNC0194-0499 and semaglutide) can reduce liver damage in patients with non alcoholic steatohepatitis (NASH). NNC0194-0499 is a new medicine which works in the liver. Semaglutide is a well-known medicine, which is already used by doctors to …
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