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Found 12 Squamous Cell Carcinoma trials

A listing of Squamous Cell Carcinoma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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60 years or above
All genders
Phase 3
Interventional
This study investigates the effectiveness and safety of an investigational medication activated by radiotherapy, with or without cetuximab, for elderly patients who cannot receive platinum-based chemotherapy. The focus is on individuals with locally advanced head and neck squamous cell carcinoma (LA-HNSCC). Participants are divided into two study arms to compare …
18 years or above
All genders
Observational
This study investigates head and neck squamous cell carcinoma (HNSCC). The purpose of this study is to understand the molecular characteristics of HNSCC by profiling biomarkers in tissue and blood samples from patients undergoing their usual care treatment.Participants in this study will have their tissue and blood samples collected for …
18 years - 74 years
All genders
Phase 1
Interventional
This study investigates head and neck squamous cell carcinoma. The purpose of this study is to evaluate the safety and effectiveness of an investigational medication when used with standard chemotherapy and radiation therapy.The study focuses on assessing how well the investigational medication works with chemoradiation therapy. It evaluates the treatment's …
18 years or above
All genders
Phase 1
Interventional
This study investigates the safety and effectiveness of an investigational oral medication designed to degrade SMARCA2 in patients with advanced or metastatic solid tumors that have a SMARCA4 mutation. The purpose of this study is to understand how the investigational medication affects the body, how it is processed by the …
18 years or above
All genders
Phase 1
Interventional
This study investigates the use of an investigational medication in comparison to primary surgery for individuals with early stage Cutaneous Squamous Cell Carcinoma (CSCC). This study aims to understand how the investigational medication affects the tumor and the body, as well as the potential side effects that may occur.Participants in …
18 years or above
All genders
Phase 1/2
Interventional
This study investigates the use of an investigational medication in patients with advanced solid tumors, specifically focusing on its effects as a single agent or in combination with other therapies. The purpose is to determine the recommended Phase II dose and to evaluate its safety, tolerability, and anti-tumor activity. The …
18 years or above
All genders
Phase 1
Interventional
This study investigates the safety and effectiveness of an investigational medication in combination with immuno-oncology agents for individuals with advanced or metastatic solid tumors that cannot be surgically removed. The purpose of this study is to understand how the investigational medication, when used alone or with other treatments like nivolumab, …
99 years or below
All genders
The purpose of this study is to determine surgical outcomes following surgical excision (MMS vs WLE) of cutaneous desmoplastic/spindle cell squamous cell carcinoma. The primary objective of this study is to determine local recurrence rates following surgical excision of cutaneous desmoplastic/spindle cell squamous cell carcinoma. Secondary objectives are to determine …
99 years or below
All genders
This study investigates the use of a device to evaluate skin lesions that may suggest conditions like melanoma, basal cell carcinoma, and squamous cell carcinoma. The purpose of this study is to assess how accurately the device can identify these conditions in patients 22 years and older.Participants will have their …
EA2192 APOLLO: A Randomized Phase II Double-Blind Study of Olaparib versus Placebo Following Curative Intent Therapy in Patients with Resected Pancreatic Cancer and a Pathogenic BRCA1, BRCA2 or PALB2 Mutation
18 years or above
All genders
Phase 2
Interventional
This study investigates the effectiveness of an investigational medication following surgery and chemotherapy in patients with pancreatic cancer who have specific genetic mutations. The study focuses on patients whose cancer has been surgically removed and who have a mutation in the BRCA1, BRCA2, or PALB2 genes. These genes are known …
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