Found 5 Thyroid Disorders trials
A listing of Thyroid Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
LCAT Deficiency Disorders: natural history and identification of biomarkers
Familial lecithin:cholesterol acyl transferase (LCAT) deficiency (FLD) is a rare, hereditary disease with no treatment. It is caused by mutations in the gene for LCAT, an enzyme that is made in the liver and plays a role in the body’s ability to process (“metabolize”) cholesterol. People with FLD have very …
Observational Characterization of the Treatment Course of Patients With Thyroid Eye Disease
This study will: • Evaluate standard-of-care (SOC) treatment for TED in a real-world setting • Evaluate effectiveness of the treatment in terms of protrusion of the eyeball (proptosis) • Show if the SOC treatment has any effect on eye anatomy and function and fi the appearance of the subject’s eyes …
Phase I Trial of GFR4 CART Cells in Adult Patients with Recurrent or Metastatic Medullary Thyroid Cancer
Phase 1
This is an open-label phase 1 study to assess the safety and feasibility of autologous T cells expressing a single-chain scFv targeting GFRa4 with tandem TCR/CD3 and 4-1BB (TCR/4-1BB) costimulatory domains (referred to as CART-GFRa4) in patients with incurable medullary thyroid cancer (MTC). This is a Phase 1 study evaluating …
GP44729
The purpose of this study is to assess the efficacy, safety, pharmacokinetics, and pharmacodynamics of subcutaneous satralizumab, a recombinant, humanized antiinterleukin-6 (IL-6) receptor monoclonal antibody, in participants with moderate-to-severe thyroid eye disease (TED).
Dosing of LT4 (DOT4)
The purpose of this study is to find the effects of taking different doses of the thyroid medication levothyroxine in older people who already take levothyroxine for hypothyroidism. Older people are more likely to have problems when their dose of levothyroxine is too strong. Allowing lower doses of levothyroxine would …
