Found 24 Liver Disorders trials
A listing of Liver Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
This is an observational study that will compare the differences in lymphatic flow and anatomy of the central lymphatic system on MRL in the liver cirrhosis patients with and without ascites. In the second part of the study, MRL anatomical and flow changes in the central lymphatic system of patients …
Familial lecithin:cholesterol acyl transferase (LCAT) deficiency (FLD) is a rare, hereditary disease with no treatment. It is caused by mutations in the gene for LCAT, an enzyme that is made in the liver and plays a role in the body’s ability to process (“metabolize”) cholesterol. People with FLD have very …
For subjects age 18 years and older who are at an increased risk for HCC and for whom HCC surveillance is appropriate, including subjects with cirrhosis or non-cirrhotic subjects with Hepatitis B. Approximately 3,000 subjects are expected to be enrolled, comprised of approximately 2,222 ultrasound surveillance subjects and 778 subjects …
The main purpose of this study is to determine if certain genes, hormones, or other factors predict the risk of developing lung vessel disease in patients with liver disease and whether they determine outcome. Patients in need of a liver transplant evaluation or have portopulmonary hypertension or are suspected of …
Determine the reproducibility of the subharmonic aided pressure estimation (SHAPE) algorithm in subjects to estimate portal pressures with an ultrasound scanner. Examine if serial SHAPE can accurately predict development of ascites and other liver related events. Use SHAPE to monitor treatment response in patients identified with portal hypertension and compare …
AL (or light chain) amyloidosis begins in the bone marrow where abnormal proteins misfold and create free light chains that cannot be broken down. These free light chains bind together to form amyloid fibrils that build up in the extracellular space of organs, affecting the kidneys, heart, liver, spleen, nervous …
Septic shock is a disease of the circulatory system representing a complication of serious infections, and is associated with a very high mortality, since around 1/3 of patients with this condition die. This disease produces a series of alterations in the body, including failure of the heart, kidneys, liver, among …
The purpose of this study is to evaluate the outcomes of liver transplant when the donor is placed on a normothermic perfusion machine prior to donation of the liver. The perfusion machine restores oxygenated blood flow to organs in the abdomen such as the liver. The use of the machine …
This is a Phase Ib/II study in participants with advanced liver cancers. Cohort 1 - participants with locally advanced or metastatic hepatocellular carcinoma (HCC) who have not received prior systemic therapy for their disease. Participants who experience loss of clinical benefit or unacceptable toxicity during Stage 1 may be eligible …
Liver metastases are a leading cause of death among patients with metastatic colorectal cancer. Duration of disease control is short following 2nd-line or later systemic therapy. Liver-directed therapy such as TACE has a higher response rate and improves PFS, but the benefit is still limited. Cancer cells escape ischemic cell …
