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Found 11 Stem Cell Transplant trials

A listing of Stem Cell Transplant medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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A Multicenter Randomized Controlled Trial of Best Available Therapy versus Autologous Hematopoietic Stem Cell Transplant for Treatment-Resistant Relapsing Multiple Sclerosis (BEAT-MS)
18 years - 55 years
All genders
The purpose of this study is to compare efficacy and safety of Autologous Hematopoietic Stem Cell Transplant (AHSCT) to best available therapy (BAT) in relapsing MS. Best available therapy is referring to the best available medications that are used to treat MS. Patients who agree to participate in the experimental …
18 years or above
All genders
Phase 3
Interventional
This study investigates the effectiveness of two different treatment regimens for patients undergoing allogeneic peripheral blood stem cell transplantation. The study focuses on patients with conditions such as acute leukemia, chronic myelogenous leukemia, myelodysplasia, and various types of lymphoma. The purpose is to compare the use of Tacrolimus, Methotrexate, and …
18 years or above
All genders
Phase 3
Interventional
This study investigates the effects of different maintenance therapies in people with newly diagnosed multiple myeloma. The purpose of this study is to compare the investigational medication teclistamab in combination with lenalidomide, teclistamab alone, and lenalidomide alone in maintaining health after a stem cell transplant.Participants will be randomly assigned to …
18 years or above
All genders
Phase 1
Interventional
This study investigates a potential treatment for Acute Myeloid Leukemia (AML). The purpose of this study is to explore the use of a modified stem cell transplant combined with engineered T cells, known as chimeric antigen receptor (CAR) T cells, to target and attack leukemia cells. CAR T cells are …
All genders
Phase 2
Interventional
This study investigates the safety of using investigational cord blood units for hematopoietic stem cell transplantation in pediatric and adult patients. The purpose of this study is to monitor and evaluate any infusion-related reactions that occur when these investigational cord blood units are administered.Participants in the study will receive investigational …
60 years or above
All genders
Observational
This study investigates the use of frailty assessments to predict outcomes for patients aged 60 years and older who are receiving treatments such as chemotherapy, CAR T-cell therapy, or allogeneic stem cell transplant for blood cancers. Frailty assessments help determine a patient's physical resilience and vulnerability, which may influence treatment …
18 years or above
All genders
Phase 1
Interventional
This study investigates the safety and feasibility of using T-cell receptor engineered donor T-cells in patients undergoing allogeneic peripheral blood stem cell transplantation. The study focuses on patients with acute myeloid leukemia (AML), myelodysplastic syndromes (MDS), or acute lymphoblastic leukemia (ALL) who receive transplants from specific types of donors. The …
18 years - 75 years
All genders
Phase 3
Interventional
This study investigates treatments for adults newly diagnosed with BCR-ABL-positive Acute Lymphoblastic Leukemia (ALL). The purpose of this study is to compare the effectiveness of a standard treatment involving chemotherapy, steroids, and a type of medicine called a tyrosine kinase inhibitor (TKI) with a treatment that adds another medicine called …
3 years - 75 years
All genders
Phase 2
Interventional
This study investigates the use of bone marrow transplantation for patients newly diagnosed with severe aplastic anemia (SAA). The study aims to determine if patients with SAA can be effectively treated with a bone marrow transplant as their first therapy option, using donors who are either haploidentical related or unrelated, …
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