Found 14 Amyloidosis trials
A listing of Amyloidosis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This open-label study is designed to evaluate the long-term safety and tolerability of acoramidis in participants with ATTR-CM, administered on a background of stable heart failure therapy. This study follows the randomized, double-blind, placebo-controlled Study AG10-301 which was designed to examine safety and efficacy in this same population.
This is a multicenter, open-label extension of the ION-682884-CS2 Study (CARDIO-TTRansform) and of the ISIS 420915-CS101 Study. Eligible participants will receive eplontersen once every 4 weeks for up to 36 months or 6 months after eplontersen is approved and available in the site's country, whichever occurs first. Participants will also …
Aim 1: To obtain measures of cerebral beta-amyloid plaques with amyloid PET (A), neurofibrillary tangles with tau PET (T), and neurodegeneration with structural MRI (N) in a cohort of older adults diagnosed with MCI or AD to evaluate this dataset with a T-N mismatch metricmodel for phenotypic discovery. The central …
The purpose of this study is to:Evaluate the efficacy of nucresiran compared to placebo on reducing all-cause mortality and cardiovascular (CV) eventsEvaluate the efficacy of nucresiran compared to placebo on additional assessments of CV events and/or deathEvaluate the efficacy of nucresiran compared to placebo on patient-reported health status and health-related …
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