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Found 29 Pancreatitis trials
A listing of Pancreatitis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study investigates the effects of an investigational medication combined with nab-paclitaxel and gemcitabine compared to a placebo with the same combination in people with untreated metastatic pancreatic ductal adenocarcinoma (PDAC) who have a specific genetic deletion called homozygous MTAP deletion. The study aims to explore the safety and efficacy …
To create a comprehensive system to collect, catalogue, and store biological specimens (tumor samples) from subjects with confirmed or suspected pancreatic cancer for future research use. To generate "tumor organoids" from these biopsy or surgical specimens. To integrate the specimen collections with clinical data to permit the most informative clinical- …
This study investigates a maintenance immunotherapy using CD40/Dectin-1 for patients with unresectable pancreatic ductal adenocarcinoma (PDA) who have not shown disease progression after 4-6 months of first-line chemotherapy. This research aims to explore the effectiveness of an investigational immunotherapy in maintaining disease stability in these patients.The study involves several procedures, …
This study investigates the effectiveness of an investigational medication combined with ipilimumab in patients with metastatic pancreatic cancer. The purpose is to understand if this combination can slow tumor growth and what side effects may occur. Participants will be placed into two study arms: Arm A will receive the investigational …
This study investigates neuroendocrine tumors. It focuses on participants who have previously received treatment for tumors that cannot be removed by surgery or have spread to other parts of the body.This study evaluates the effectiveness of an investigational medication compared to everolimus. It examines how well the treatments work and …
This study investigates the effects of an investigational medication on patients with advanced solid tumors that have a KRAS G12D mutation. The purpose is to understand the safety and effectiveness of the investigational medication when used alone and in combination with other treatments.Participants in the study will receive the investigational …
This study investigates circulating biomarkers in patients with pancreatic adenocarcinoma. The purpose of this study is to collect blood samples from patients to evaluate these biomarkers, which are substances that can be measured in the blood and may provide information about the cancer.Participants will undergo a procedure to collect blood …
This study investigates the safety and clinical activity of an investigational medication in participants with advanced solid tumors that have a specific genetic mutation known as KRAS G12C. The purpose of this study is to evaluate how the investigational medication works in different phases, including dose escalation and expansion, to …
The purpose of the Pancreatic Cancer Early Detection (PRECEDE) Consortium is to conduct research on multiple aspects of early detection and prevention of pancreatic ductal adenocarcinoma (PDAC) by establishing a multi-site cohort of individuals with family history of PDAC and/or individuals carrying pathogenic/likely pathogenic germline variants (PGVs) in genes linked …
Single patient compassionate use protocol. Received palliative first-line treatment with FOLFIRINOX/FOLFIRI from 6/2017 through 4/2018 at which time her disease remained stable. The patient was suffering from cumulative chemotherapy toxicities and therefore elected to enroll in UPCC 35217, a trial of maintenance niraparib with either nivolumab or ipilimumab in patients …
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