Search filters

Filters
Clear All

Phase

  • 3
  • 1
  • 1
  • 1
  • 3
  • 10
  • 3
  • 10

Found 10 Gliomas trials

A listing of Gliomas medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Sort by:
18 years or above
All genders
Phase 2
Interventional
This study investigates the effects of a combination of investigational medication and PD-1 inhibition on recurrent IDH-mutant glioma, a type of brain tumor. The purpose of this study is to see if this combination can stimulate an immune response against the tumor.Participants in this study will undergo different procedures depending …
UPCC 21317 Detection of Cell-Free Circulating Tumor DNA in Patients with Histopathologically/Molecularly Proven or Radiographically Suspected Glial Tumors
99 years or below
All genders
Glioblastoma (GBM) is the most common primary brain tumor in adults and is uniformly fatal. During standard adjuvant treatment for GBM following initial surgical resection of the tumor, patients are treated with a combination of radiation and chemotherapy. During and after this adjuvant treatment, patients are monitored for disease progression …
99 years or below
All genders
Coordinate with the patient end-of-life care teams to arrange autopsy for patients currently or previously enrolled in UPCC 16321.
18 years or above
All genders
Phase 1
Interventional
This study investigates treatment options for individuals with recurrent or progressive IDH-1 mutant glioma, a type of brain tumor. The purpose is to evaluate the safety and effects of combining an investigational medication with another treatment. Participants will be divided into two phases: a Safety Lead-In phase to determine safe …
UPCC 09321 Whole-Brain Spectroscopy Guided Personalized Mapping Of Transducer Arrays For Glioblastoma Patients Receiving Tumor Treating Fields
22 years or above
All genders
Interventional
This study investigates the effectiveness of personalized mapping techniques for patients with Glioblastoma, a type of brain cancer. The purpose of this study is to compare two different mapping methods used in tumor treating fields (TTFields) therapy, which is a type of electrical therapy that has shown to improve survival …
99 years or below
All genders
PURPOSE We would like to accrue patients consecutively over a several year period in order to collect tissue from many histopathologic subsets of nervous system tumors. Primary brain tumors occur nationally at a rate of approximately 17,000 new cases annually and within this group there are numerous subtypes. At the …
UPCC 20319 GBM AGILE: Global Adaptive Trial Master Protocol: An International, Seamless Phase II/III Response Adaptive Randomization Platform Trial Designed To Evaluate Multiple Regimens In Newly Diagnosed and Recurrent GBM
18 years or above
All genders
Phase 2/3
Interventional
This study investigates therapies for glioblastoma, a type of brain cancer. The purpose of this study is to evaluate multiple therapies for newly diagnosed and recurrent glioblastoma using a response adaptive randomization platform. This method assigns participants to different study arms based on their performance, aiming to identify effective treatments …
18 years or above
All genders
Phase 1
Interventional
This study investigates the safety and feasibility of a treatment involving specialized T cells, known as CART-EGFR-IL13Ra2 cells, for patients with recurrent glioblastoma. The study focuses on patients whose tumors have a specific genetic feature called EGFR amplification.Participants in this study will receive an infusion of their own T cells …
18 years or above
All genders
Phase 1
Interventional
This study investigates the safety of using a type of immune cell therapy in patients with glioblastoma. The study will use T cells, which are a type of white blood cell, that have been modified to target specific proteins on cancer cells. These proteins are known as EGFR and IL13Ra2. …
18 years - 100 years
All genders
Phase 1/2
Interventional
This study investigates an investigational medication for adults with advanced MTAP-null solid tumors. The study aims to evaluate the safety and tolerability of the investigational medication alone and in combination with another treatment called docetaxel.Participants will receive the investigational medication orally, and their health will be monitored to assess the …