Found 7 Metastatic Cancer trials

A listing of Metastatic Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

ADMIRE Study

22-99 years

Female

The objective of this study is to establish reasonable assurance of safety and effectiveness to support a premarket application (PMA) to the U.S. FDA for the Cortiva Allograft Dermis, a human acellular dermal matrix (ADM), when used on label as an adjunct in two-stage breast reconstruction. The primary safety endpoint …

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A Phase 1/2 Study of VX-670 in Adult Subjects with Myotonic Dystrophy Type 1

99 years and younger

All genders

Please refer to Protocol V2.2, Version date 12Feb2024, Section 6.2 (Study Objectives Part B) on page 28 for a full list of primary, secondary, and other exploratory objectives. Please refer to Protocol V2.2, Version date 12Feb2024, Section 7.2 (Study Endpoints Part B) on page 29 for a full list of …

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GOG 3096: Dose Optimization and Phase 3 Study of R-DXd versus Investigators Choice of Chemotherapy in Platinum-resistant Ovarian Cancer

99 years and younger

All genders

Phase 2: To evaluate BICR-assessed objective response rate at each dose level of R-DXd. Phase 3:To evaluate BICR-assessed objective response rate with R-DXd treatment compared with investigator's choice of paclitaxel, PLD, gemcitabine, or topotecan. Objectives, outcome measures, and endpoints are located in Tables 3.1 and 3.2 of the protocol. Phase …

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SCD Depo

99 years and younger

All genders

To assess prospectively the frequency of acute vaso-occlusive episodes (VOEs) and VOE-associated biomarkers. The secondary outcome is VOE-related biomarker levels during each phase. During both the baseline and intervention study phases, participants will provide weekly reports via electronic survey of vaso-occlusive pain. VOE will be defined as self-reported typical SCD …

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Adjuvant Concurrent Immunotherapy and Radiotherapy for the Treatment of Bladder Cancer

99 years and younger

All genders

The primary objective of this Phase I study is to establish the safety of adjuvant concurrent radiation therapy and immunotherapy. Safety will be based on acute grade 3 or higher pelvic radiation related toxicity. Secondary objectives are to estimate late toxicities, quality of life, locoregional and distant failure and overall …

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HEAL (Heart Evaluation of Arrhythmia and Lipomatosis) Study

99 years and younger

All genders

PURPOSE We aim to conduct a prospective observational study to test the central hypothesis that myocardial LM begins early after STEMI, as a response to myocardial hemorrhage and reperfusion injury, and determines future susceptibility to malignant arrhythmia. Study participants will be 175 (allowing for 25 dropouts) men and women 2 …

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TumorGlow in Pulmonary Metastasectomy for Sarcomas

99 years and younger

All genders

This is a phase 3, multi-center, randomized, single dose, open-label study to determine the efficacy of a single dose, 5 mg/kg of ICG (TumorGlow) used with Near Infrared (NIR) fluorescent to detect clinically significant event (CSE) for subjects with suspected metastatic sarcoma to the lung scheduled to undergo thoracic surgery …

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