Found 10 Cardiomyopathy trials
A listing of Cardiomyopathy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
The purpose of this registry is to understand the safety and effectiveness of various medications used in treating the condition of symptomatic obstructive hypertrophic cardiomyopathy (HCM), a type of heart disease that causes the muscular wall in the chambers of the heart to thicken which can cause blood flow in …
This open-label study is designed to evaluate the long-term safety and tolerability of acoramidis in participants with ATTR-CM, administered on a background of stable heart failure therapy. This study follows the randomized, double-blind, placebo-controlled Study AG10-301 which was designed to examine safety and efficacy in this same population.
This study will focus on fat buildup inside the heart muscle, a newly recognized factor that makes patients vulnerable to such fast heart rates, or ventricular tachycardia, after a heart attack. This work may identify more successful strategies for curing dangerously fast heart rates. Adult subjects with prior history of …
This is a prospective, multicenter observational study to identify clinical, genetic and imaging predictors of clinical outcome in patients with suspected non-compaction cardiomyopathy Many healthy people have increased trabeculations without consequences, however, some may develop blood clots, heart rhythm disorders or heart failure later in life. Currently we cannot predict who …
This study aims to identify genotypic and phenotypic characteristics that are associated with the clinical heterogeneity and outcomes of hypertrophic cardiomyopathy (HCM), using the Sarcomeric Human Cardiomyopathy Registry (SHaRe).
This is a multicenter, open-label extension of the ION-682884-CS2 Study (CARDIO-TTRansform) and of the ISIS 420915-CS101 Study. Eligible participants will receive eplontersen once every 4 weeks for up to 36 months or 6 months after eplontersen is approved and available in the site's country, whichever occurs first. Participants will also …
The purpose of the study is to test the use of a drug called bromocriptine for women who have a condition called Peripartum cardiomyopathy or PPCM. PPCM means you have a weak heart after giving birth. The study will look at how the heart muscle improves in women taking bromocriptine …
This is a Phase 3, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of amyloid depleter ALXN2220 compared to placebo in adult participants with Transthyretin Amyloid Cardiomyopathy (ATTR-CM).Approximately 1000 participants will be enrolled and randomized to receive either ALXN2220 or placebo in a 2:1 ratio. Participants will receive …
At home care (AHC) Artificial Intelligence Electrocardiogram (AI-ECG) can improve cardiac screening by echocardiogram for first degree relatives (FDR) of patients with dilated cardiomyopathy (DCM). Probands will contact their FDRs about testing with an AI-ECG mobile device. This study compares the impact of screening FDR of probands with DCM using …
To determine the changes in symptoms and functional limitations in patients with symptomatic hypertrophic cardiomyopathy (HCM) treated with sotagliflozin as compared to placebo.
