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Found 22 Pancreatic Cancer trials
A listing of Pancreatic Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study investigates the effectiveness of adding an investigational medication to the standard treatment for patients with metastatic pancreatic cancer who have specific genetic mutations known as BRCA1 or BRCA2. The purpose of this study is to see if the combination of an investigational medication with olaparib, a targeted therapy …
This study investigates the effectiveness of an investigational medication combined with ipilimumab in patients with metastatic pancreatic cancer. The purpose is to understand if this combination can slow tumor growth and what side effects may occur. Participants will be placed into two study arms: Arm A will receive the investigational …
To create a comprehensive system to collect, catalogue, and store biological specimens (tumor samples) from subjects with confirmed or suspected pancreatic cancer for future research use. To generate "tumor organoids" from these biopsy or surgical specimens. To integrate the specimen collections with clinical data to permit the most informative clinical- …
This study investigates the safety, tolerability, and preliminary effects of an investigational medication combined with gemcitabine in patients with advanced pancreatic cancer. The study is for those who have already been treated with chemotherapy that includes 5-fluorouracil and have not responded to it.Participants will first receive a single dose of …
This study investigates the safety and effects of an investigational radioligand therapy in adults with advanced or metastatic solid tumors that have high levels of fibroblast activation protein (FAP). The study aims to understand how the investigational therapy interacts with FAP. The purpose of this study is to evaluate the …
This study investigates the treatment of KRAS-mutated cancers. The purpose of this study is to evaluate the safety and preliminary effectiveness of a new investigational treatment in patients with specific types of cancer that have a KRAS mutation.The study focuses on assessing the safety and how well the investigational treatment …
This study investigates the safety and effects of an investigational medication in adults with carcinoid syndrome. The purpose of this study is to evaluate how the investigational medication works in the body and its safety for people with this syndrome.Participants will first be randomly assigned to receive either the investigational …
The purpose of this study is to investigate the effectiveness of an investigational medication in patients with HER2-positive solid tumors that are locally advanced, unresectable, or metastatic. In this study, HER2-positive is identified as IHC 3+. The study focuses on patients who have previously received systemic treatment for their condition …
This study investigates how genetic testing can guide cancer treatment choices for patients with advanced solid tumors. The purpose is to use the genetic information from patients' tumor cells to match them with investigational combination therapies that target specific genetic mutations. This approach aims to control tumor growth and improve …
This study investigates the effects of an investigational medication combined with nab-paclitaxel and gemcitabine compared to a placebo with the same combination in people with untreated metastatic pancreatic ductal adenocarcinoma (PDAC) who have a specific genetic deletion called homozygous MTAP deletion. The study aims to explore the safety and efficacy …
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