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Found 82 Uterine Fibroids trials

A listing of Uterine Fibroids medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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18 years or above
All genders
Phase 2
Interventional
This study investigates the effectiveness of different treatment combinations for Stage I HER2-positive breast cancer. The purpose of this study is to compare the side effects and long-term benefits of two different HER2-directed therapies used after surgery. Participants will be randomly assigned to one of two study arms: one receiving …
18 years or above
All genders
Phase 2
Interventional
This study investigates the effectiveness of an investigational medication combined with ipilimumab in patients with metastatic pancreatic cancer. The purpose is to understand if this combination can slow tumor growth and what side effects may occur. Participants will be placed into two study arms: Arm A will receive the investigational …
18 years or above
All genders
Phase 1/2
Interventional
This study investigates an investigational medication designed to treat patients with advanced or metastatic solid tumors. The purpose of this study is to discover if the investigational medication can slow or stop cancer growth and to learn about its safety. The study will focus on various types of advanced cancers, …
UPCC 16121 Saci-IO TNBC: Randomized Phase II Study of Sacituzumab Govitecan With or Without Pembrolizumab in PD-L1-Negative Metastatic Triple Negative Breast Cancer (TNBC)
18 years or above
All genders
Phase 2
Interventional
This study investigates the safety and effectiveness of an investigational treatment for patients with metastatic triple-negative breast cancer (TNBC) that is PD-L1-negative. The purpose of this study is to evaluate Sacituzumab Govitecan, alone or in combination with Pembrolizumab, in delaying the progression of this cancer.Participants will undergo various study procedures, …
18 years or above
All genders
Phase 1/2
Interventional
This study investigates an investigational medication designed to treat patients with advanced or metastatic solid tumors. The purpose of the study is to evaluate the safety, tolerability, pharmacokinetics, and preliminary efficacy of this medication both as a standalone treatment and in combination with other agents. The study is focused on …
18 years or above
All genders
Phase 2
Interventional
This study investigates the safety and effectiveness of two investigational medications in treating HER2-negative metastatic breast cancer. The study involves two investigational medications given in sequence, either trastuzumab deruxtecan followed by datopotamab deruxtecan or vice versa, to understand if this approach works for patients who have already tried other similar …
18 years or above
All genders
Phase 1/2
Interventional
This study investigates the use of an investigational medication, a monoclonal antibody targeting Tumor Necrosis Factor Receptor 2 (TNFR2), in people with advanced malignancies. The purpose of the study is to evaluate the safety and tolerability of the investigational medication both alone and in combination with pembrolizumab, a type of …
18 years or above
All genders
Phase 1
Interventional
This study investigates the use of an investigational medication in comparison to primary surgery for individuals with early stage Cutaneous Squamous Cell Carcinoma (CSCC). This study aims to understand how the investigational medication affects the tumor and the body, as well as the potential side effects that may occur.Participants in …
UPCC 12420 A Phase 2, Open- Label, Single-Arm, Multicohort, Multicenter Trial to Evaluate the Efficacy and Safety of JCAR017 in Adult Subjects with Relapsed or Refractory Indolent B-Cell Non-Hodgkin Lymphoma (NHL)
18 years or above
All genders
Phase 2
Interventional
This study investigates the efficacy and safety of an investigational medication in adults with relapsed or refractory indolent B-cell Non-Hodgkin Lymphoma (NHL), specifically follicular lymphoma (FL) and marginal zone lymphoma (MZL). The purpose of this study is to understand how well the investigational medication works in treating these types of …
18 years or above
Female
Phase 3
Interventional
This study investigates the treatment of advanced or recurrent endometrial cancer with proficient mismatch repair (pMMR). In pMMR endometrial cancer, certain normal proteins are present in the cancer cells. This condition can be advanced, meaning the cancer has spread beyond the uterus, or recurrent, meaning it has returned after treatment. …