Found 4 Endometrial Cancer trials

A listing of Endometrial Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Testing Different Amounts of the Combination of Drugs M1774 and ZEN-3694 for the Treatment of Recurrent Ovarian and Endometrial Cancer (NRG-GY031)

18-99 years

Female

Phase 1

To determine the maximum tolerated dose (MTD) and the dose-limiting toxicities (DLTs) for combination of ATR inhibitor (M1774) and BET inhibitor (ZEN003694) in women with recurrent clear cell, endometrioid, and platinum resistant high grade serous ovarian carcinoma (HGSOC) and clear cell and endometrioid endometrial carcinoma irrespective of ARID1A status.The target …

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A Study of XmAb20717 (Vudalimab)in Patients With Selected Advanced Gynecologic and Genitourinary Malignancies (Xencor)

18 years and older

All genders

Phase 2

The purpose of the study is to assess whether an investigational drug, called XmAb20717, has any effects on certain types of cancers and if it is safe and well tolerated.

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A Study of CPI-0209 in Patients with Advanced Solid Tumors and Lymphomas (CPI 0209)

18-99 years

Female

Phase 1/2

First-in-human, open-label, sequential dose escalation and expansion study of CPI-0209 in patients with advanced solid tumors and lymphomas. CPI-0209 is a small molecule inhibitor of EZH2.

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GEN1047 for Solid Tumors (GENMAB)

18-99 years

Female

Phase 1/2

The overall objective of the study is to determine the maximum tolerated dose/maximum administered dose and to characterize the safety profile of GEN1047. The primary outcome variables are, dose limiting toxicities, adverse events and safety laboratory parameters as well as objective response rate based on RECIST v1.1. The secondary outcome …

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