Found 12 Dementia trials
A listing of Dementia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This research is being done to study a new way to treat FTD in patients who have the GRN mutation. This process is called “gene therapy”. Gene therapy is an experimental technique that aims to replace the gene that is not working properly with a version of the gene that …
This study investigates the presence of certain brain proteins in people with conditions like Progressive Supranuclear Palsy, Corticobasal Syndrome, genetic Frontotemporal Lobar Degeneration, Parkinson's Disease, Alzheimer's Disease, and healthy individuals. These conditions are collectively known as tauopathies.The study evaluates how a special substance, which can be seen in brain scans, …
To assess the effect of donanemab versus placebo on cognitive and functional progression in participants with established alpha-synuclein and amyloid co-pathology
This study investigates the use of behavioral economics and implementation science to improve the delivery of genomic medicine within a diverse health system. The purpose of this study is to explore how non-geneticist clinicians and patients can be encouraged, through nudges, to utilize genetic testing in situations where it can …
The study is at the Penn Memory Center at the University of Pennsylvania and is under the direction of David Wolk, M.D.. We are currently recruiting normal control participants ages 75 years and older. The purpose of this study is to collect, store and analyze cognitive data and biological samples, …
The primary objective of the IMPROVE-AD trial is to determine whether an upfront invasive strategy of TEVAR plus medical therapy reduces the occurrence of a composite endpoint of all-cause death or major aortic complications compared to an upfront conservative strategy of medical therapy with surveillance for deterioration in patients with …
The Alzheimer's Network for Treatment and Diagnostics (ALZ-NET) will collect data from individuals evaluated for or receiving treatment with novel (or new) FDA-approved therapies for Alzheimer's disease (AD). It will follow and record information about people's health, safety, brain scans, and long-term health outcomes during their regular memory care.
We are conducting research studies on how immune system cells contribute to inflammatory conditions of the nervous system, such as multiple sclerosis, neuromyelitis optica (NMO), encephalitis, head injury, epilepsy, Parkinson's disease (PD), Alzheimer's disease (AzD), Lou Gherig's disease (amyotrophic lateral sclerosis; ALS) frontotemporal dementia (FTD) and others. This includes investigating …
The purpose of this study is to validate a video-administered cognitive assessment for use by the Alzheimer's Disease Research Centers and other research programs whose activities have been interrupted by the COVID19 pandemic, as well as for use in future initiatives when remote testing will enhance achievement of scientific goals. …
The goal of this research is to collect Tau PET imaging in cognitively normal older adults and patients with Mild Cognitive Impairment (MCI) in the NACC study, to determine relationship to clinical, cognitive, and other biomarker data. Findings from this study will likely provide insight into the mechanisms and distinctions …
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