Found 11 Colon Cancer trials
A listing of Colon Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Collection of Samples from the United States Population for Optimization and Evaluation of Colorectal Cancer (CRC) Plasma Circulating Free-DNA (cfDNA) Marker Panel Performance
This study is designed to prospectively collect blood samples and clinical data from subjects that have a suspected advanced adenoma or have been newly diagnosed with colorectal cancer and scheduled for resection surgery, and subjects who are at average risk of colorectal cancer and who are scheduled for routine colonoscopy …
UPCC 11220: BESPOKE Study of ctDNA Guided Therapy in Colorectal Cancer
The study will enrollsubjects who have undergone surgery for stage II or III colorectal cancer and who have residual FFPE tissue available will provide FFPE and whole blood samples. Subjects will receive SIGNATERA test results and may be recommended for adjuvant chemotherapy or observation by their treating clinician.The study also …
NRG-GI008: Colon Adjuvent Chemotherapy Based on Evaluation of Residual Disease (Circulate-US)
Phase II and III: To compare time to DFS event (recurrence, second primary colorectal cancer or death) in ctDNA (+ve) cohort following resection of colon cancer treated with 5-FU (orcapecitabine) and oxaliplatin x 6 months or 5-FU, oxaliplatin and irinotecan x 6 months.
TACE Ax HCQ: Phase IB Study of Hepatic Chemoembolization Plus Axitinib and Hydrochlorquine for Liver-Dominant Metastatic Adenocarcinoma Of The Colon And Rectum
Phase 1
Liver metastases are a leading cause of death among patients with metastatic colorectal cancer. Duration of disease control is short following 2nd-line or later systemic therapy. Liver-directed therapy such as TACE has a higher response rate and improves PFS, but the benefit is still limited. Cancer cells escape ischemic cell …
NRG-GI008: Colon Adjuvant Chemotherapy Based on Evaluation or Residual Disease (Circulate-North America) (NRG-GI008)
Phase 2/3
This Phase II/III trial will evaluate the what kind of chemotherapy to recommend to patients based on the presence or absence of circulating tumor DNA (ctDNA) after surgery for colon cancer.This study is Enrolling by Invitation only at Lancaster General Health - ABBCI.
UPCC 19222: A Phase 2, Randomized, Open-Label Study Evaluating the Safety and Efficacy of Magrolimab in Combination With Bevacizumab and FOLFIRI Versus Bevacizumab and FOLFIRI in Previously Treated Advanced Inoperable Metastatic Colorectal Cancer (mCRC
To evaluate the safety, tolerability, and recommended Phase 2 dose (RP2D) of magrolimab in combination with bevacizumab and FOLFIRI (5-fluorouracil [5-FU], irinotecan, and leucovorin [LV]) in previously treated patients with advanced inoperable metastatic colorectal cancer (mCRC). We would like to rely on Advarra as the IRB of record for this …
S2107 Randomized Phase II Trial of Encorafenib and Cetuximab with or Without Nivolumab (NSC #748726) for Patients with Previously Treated, Microsatellite Stable, BRAFV600E Metastatic and/or Unresectable Colorectal Cancer
This phase II trial tests whether adding nivolumab to the usual treatment (encorafenib and cetuximab) works better than the usual treatment alone to shrink tumors in patients with colorectal cancer that has spread to other places in the body (metastatic) or that cannot be removed by surgery (unresectable) and whose …
UPCC 09223: A Phase 2 Clinical Trial Investigating Oncolytic Immunotherapy in Combination with Atezolizumab and bevacizumab for the Treatment of Patients with Advanced Microsatellite Stable and Mismatch Repair Proficient Colorectal Carcinoma
Please refer to Section 3.1 of the full protocol (Objectives and Endpoints) Please refer to Section 3.1 of the full protocol (Objectives and Endpoints) Please refer to Section 3.1 of the full protocol (Objectives and Endpoints)
URBI Study
Primary Objective: Determine if high definition white light colonoscopy (HDWLC) using a limited biopsy strategy is non-inferior to HDWLC using a random biopsy strategy to detect dysplasia or sessile serrated adenoma (SSA) in patients with IBD. Secondary objectives: 1. Determine if HDWLC using a limited biopsy strategy is superior to …
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