Found 205 Type 2 Diabetes Mellitus trials
A listing of Type 2 Diabetes Mellitus medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
The main purpose of this study is to see whether inhaling this combination of drugs in RSP-1502 has an acceptable safety profile and works better compared to inhaling tobramycin alone when treating participants with Cystic Fibrosis and chronic Pseudomonas aeruginosa lung infection. Procedures include spirometry, ECG, sputum collection, and pharmacokinetic …
This is a 12-month, multicenter, randomized, double-blind, placebo-controlled Phase 3 study to evaluate the safety and efficacy of daily subcutaneous metreleptin treatment in subjects with Familial Partial Lipodystrophy (FPLD). Subjects will be assigned to 1 of 3 groups depending on HbA1c and fasting TGs levels. Participants will complete 10 visits …
The objectives of this Phase 1/2 prospective interventional trial are to: 1. Evaluate the safety, tolerability, and immunogenicity of a single dose of 4D-710 delivered via nebulization 2. Identify a recommended phase 2 dose (RP2D) for further evaluation 3. Evaluate 4D-710 target gene transduction/expression in bronchoscopic samples (Dose Exploration) and …
Researchers hope to learn more about BMS 986278. The study treatment will be tested at doses of either 120 mg or 60 mg, compared to placebo. There will be 2 cohorts and up to 1185 subjects participating.
Aim: To conduct a pilot open-label study of semaglutide in lung transplant candidates with obesity. - We will get an estimate of recruitment fraction and retention on study drug. - We will determine preliminary effect estimates of change in weight, percent body fat, skeletal muscle mass, and circulating levels of …
This phase 3 study will evaluate bexotograst in patients with IPF. The study will include a CT, PEs, lung function testing, EKGs, vital signs, questionnaires, and safety labs, as well as PK and PD testing.
This protocol will assess the safety and tolerability of BMS 986278 in patients with PPF. It will involve PEs, safety labs, clinical labs, pulmonary tests, EKGs, HRCTs, vital signs, and 6MWTs.
The Investigation Device Exemption (IDE) study will evaluate the safety of delivering Aliya PEF in patients with metastatic cancer within the lungs or stage IV non-small cell lung cancer NSCLC) who are treatment-naïve and indicated for first-line standard of care (SOC) cancer therapy.
Determine safety and tolerability of IV administered doses of CMTX-101. Determine safety and tolerability of IV administered doses of CMTX-101. Assess the PK of different doses of CMTX-101. Evaluate immunogenicity (i.e., development of anti-drug antibodies [ADA] and neutralizing antibodies [Nabs]) of a single IV administered dose of CMTX-101. Assess the …
