Found 26 Healthy Volunteer trials
A listing of Healthy Volunteer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used in the treatment of pain and inflammation. Mounting evidence indicates that rectal administration of NSAIDs is also effective in preventing pancreatitis following endoscopic retrograde cholangiopancreatography (ERCP) by an unknown mechanism. Alterations in the salivary and fecal microbiome have been observed in patients with …
The aim of this study is to biobank blood and stool samples of healthy individuals receiving β-hydroxybutyrate (BHB) supplementation. Additionally, this study will determine whether BHB supplementation increases serum BHB levels and leads to changes in T cell phenotype, including composition (i.e. CD4/CD8), and cytokine secretion. BHB supplementation will be …
We are conducting research studies on how immune system cells contribute to inflammatory conditions of the nervous system, such as multiple sclerosis, neuromyelitis optica (NMO), encephalitis, head injury, epilepsy, Parkinson's disease (PD), Alzheimer's disease (AzD), Lou Gherig's disease (amyotrophic lateral sclerosis; ALS) frontotemporal dementia (FTD) and others. This includes investigating …
Assess magnitude of the baseline differences between participants with early Huntington's Disease & healthy participants with respect to measures of cognitive performance, evaluate effect of SAGE-718 on cognition & functioning outcomes in participants with HD & to evaluate safety & tolerability of SAGE718 in participants with HD, evaluate reliability & …
Primary Objectives Determine biodistribution of the radioactive investigational drug, 11C M503 and calculate human dosimetry (at least 10 male and female participants). Demonstrate the feasibility of imaging the brain with the novel imaging agent 11C M503 Determine the most appropriate data analysis methodology. Determine whether there is selective uptake of …
The research study is being conducted to test if a form of noninvasive brain stimulation,called transcranial alternating current stimulation (tACS), will improve a person’s abilityto name objects more than fake tACS. TACS is a technique by which small electriccurrents are applied to the scalp. This creates coordinated brain activity across …
Primary Objectives Determine biodistribution of the radioactive investigational drug, 11C HY-2-15 and calculate human dosimetry (at least 10 male and female participants). Demonstrate the feasibility of imaging the brain with the novel imaging agent 11C HY-2-15 Determine the most appropriate data analysis methodology. Determine whether there is selective uptake of …
Primary objective is to: To assess rates of complete myocardial glucose suppression (MGS) with 7 days of sotagliflozin 400 mg QD among healthy volunteers on a background of 1 day of the KD (N=20) and 3 days of the KD (N=20). Secondary objective is to: To investigate the relationship between …
Normal 0 false false false EN-US X-NONE X-NONE The research study is being done to test the performance of a new type of whole-body imaging device called a Positron Emission Tomography (PET) long-axial field-of-view scanner, called the PennPET Explorer, that has been developed at the University of Pennsylvania and is …
![Imaging inflammation in individuals with Alcohol Use Disorder: an [18F]NOS study](/media/img/trial_thumbnails/img/siteimg/19_y57mJN5.png)
This is a research study for people ages 18-65 to learn more about how regular alcohol use affects inflammation in the brain and other organs. We will study this using a Positron Emission Tomography (PET/CT) scan using a radioactive imaging drug called [18F]NOS. [18F]NOS is an experimental radioactive molecule used …
