A listing of Addictions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
This study is a phase IV, two-arm, randomized, double-blind, placebo-controlled study to assess whether individuals identified as primarily reward drinkers are significantly more likely to reduce heavy drinking if they receive XR-NTX than a matching placebo injection. Study subjects will receive monthly injections of long-acting injectable naltrexone 380 mg (4 …
The goal is to conduct a screening procedure to be used in evaluating individuals either with or without an alcohol use disorder (AUD) to determine whether it is safe and appropriate for them to participate in a clinical trial, imaging study, genetic study, or other research protocol that matches their …
The goal of this study is to evaluate individuals with and without substance use disorder (SUD) to determine whether it is safe and appropriate for them to participate in a clinical trial, imaging study, or other research protocol that matches the participants’ interests and eligibility. Our goal is to enroll …
Have problem with opiates? You may qualify for the study if you are: - Between 18–60 years old - In treatment or seeking treatment for opioid use problems - Willing to complete one MRI scan of the brain The study will investigate the psychological and brain mechanisms of opioid use disorder. There will be …
The purpose of this study is to examine the effect of changes in cigarette package color on smoking behaviors, harm exposure, and risk perceptions when using low nicotine content (LNC) cigarettes.
The goal of this project is to test a novel approach to initiating buprenorphine treatment for OUD that can be used in outpatient setting without requiring or precipitating opioid withdrawal. Subjects will be randomized to one of two arms: standard initiation, in which subjects will start buprenorphine after 8 hours …
The research study is being conducted to better understand the effects of ketosis on brain functioning after three separate 3-day dietary interventions and the acute effects of alcohol during three separate MRI and lab visits after consuming about 4-5 alcohol beverages.
This study will examine the safety and effectiveness of lofexidine/pregabalin compared to lofexidine/placebo for managing opioid withdrawal in an outpatient settings. The study timeline is Screening from 1-30 days; dosing for 1-7 days, and a sttudy medication taper on days 8, 9, 10; Day 8 is also 1st dose of …
To examine the effects of ketone supplement, Kenetik (KS) three times daily (TID), verse placebo, on the need for benzodiazepines and CIWA scores, while undergoing in-patient acute withdrawal management.To test the effects of Ketone Supplementation (KS) Kenetik in reducing alcohol withdrawal signs and symptoms and the need for medications to …
The 5-year K01 Mentored Research Scientist proposal will employ brain, neurocognitive, and computational tools (e.g., machine learning) to understand the impact of opioid-use disorder (OUD) and common co-occurring issues on executive function and clinical outcomes.