Found 12 Malignant Melanoma trials
A listing of Malignant Melanoma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study investigates solid tumors. Participants will provide clinical data and biological samples to support cancer biomarker research.The focus of this study is to evaluate the development of tests for cancer detection and assessing the risk of cancer recurrence.Who can participate: Adults aged 18 and older with a confirmed diagnosis …
This study investigates the safety and efficacy of an investigational medication for patients who require treatment with a product that does not meet commercial release standards but is deemed safe for use in clinical settings. The purpose of this study is to provide access to this investigational medication for patients …
This study investigates the safety and tolerability of genetically modified autologous T cells in patients with recurrent or refractory solid tumors. The T cells are engineered to express a receptor that recognizes a specific cancer-related protein called PRAME, which is often found in melanoma and other solid tumors. The study …
The purpose of this study is to investigate the effects of immune checkpoint inhibitors (ICI) on the heart and circulatory system in patients with breast cancer or non-small cell lung cancer. This study focuses on understanding how these medications, which are used in cancer treatment, might impact heart health. An …
This study investigates the use of a device to evaluate skin lesions that may suggest conditions like melanoma, basal cell carcinoma, and squamous cell carcinoma. The purpose of this study is to assess how accurately the device can identify these conditions in patients 22 years and older.Participants will have their …
This study investigates the safety, tolerability, and anti-tumor activity of an investigational medication in adult patients with solid tumors that express MAGE-A4, a specific tumor-associated antigen. The study focuses on individuals with the HLA-A*02:01 tissue marker, which is necessary for participation.Participants will undergo various study procedures to evaluate the maximum …
This study investigates the use of an investigational medication, a monoclonal antibody targeting Tumor Necrosis Factor Receptor 2 (TNFR2), in people with advanced malignancies. The purpose of the study is to evaluate the safety and tolerability of the investigational medication both alone and in combination with pembrolizumab, a type of …
This study investigates the effectiveness of two different radiation therapy approaches, fractionated stereotactic radiosurgery (FSRS) and single fraction stereotactic radiosurgery (SRS), in treating patients with cancer that has spread to the brain. SRS involves delivering a single large dose of radiation to the tumor, while FSRS spreads the dose over …
The purpose of this study is to investigate the effectiveness of an investigational medication in patients with HER2-positive solid tumors that are locally advanced, unresectable, or metastatic. In this study, HER2-positive is identified as IHC 3+. The study focuses on patients who have previously received systemic treatment for their condition …
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