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Found 4 Thyroid Disease trials

A listing of Thyroid Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 LCAT Deficiency Disorders: natural history and identification of biomarkers
1 - 99
All genders
Familial lecithin:cholesterol acyl transferase (LCAT) deficiency (FLD) is a rare, hereditary disease with no treatment. It is caused by mutations in the gene for LCAT, an enzyme that is made in the liver and plays a role in the body’s ability to process (“metabolize”) cholesterol. People with FLD have very …
 Phase I Trial of GFR4 CART Cells in Adult Patients with Recurrent or Metastatic Medullary Thyroid Cancer
18 - 99
All genders
Phase 1
This is an open-label phase 1 study to assess the safety and feasibility of autologous T cells expressing a single-chain scFv targeting GFRa4 with tandem TCR/CD3 and 4-1BB (TCR/4-1BB) costimulatory domains (referred to as CART-GFRa4) in patients with incurable medullary thyroid cancer (MTC). This is a Phase 1 study evaluating …
99 or below
All genders
This phase III trial compares the effect of cabozantinib versus combination dabrafenib and trametinib for the treatment of patients with differentiated thyroid cancer that does not respond to treatment (refractory) and which expresses a BRAF V600E mutation. We would like to rely on CIRB as the IRB of record for …
 Dosing of LT4 (DOT4)
65 - 100
All genders
The purpose of this study is to find the effects of taking different doses of the thyroid medication levothyroxine in older people who already take levothyroxine for hypothyroidism. Older people are more likely to have problems when their dose of levothyroxine is too strong. Allowing lower doses of levothyroxine would …