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Found 26 Ovarian Cancer trials
A listing of Ovarian Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study investigates the safety and effectiveness of an investigational medication in patients with locally advanced or metastatic solid tumors that have a specific mutation in the TP53 gene called Y220C. The study is divided into different phases to assess the medication alone and in combination with another treatment. The …
This study investigates the effectiveness of two surgical procedures in reducing the risk of ovarian cancer in individuals with BRCA1 mutations. The purpose of this study is to compare bilateral salpingectomy, which involves removing the fallopian tubes, with bilateral salpingo-oophorectomy, which involves removing both the fallopian tubes and ovaries. These …
This study investigates how genetic testing can guide cancer treatment choices for patients with advanced solid tumors. The purpose is to use the genetic information from patients' tumor cells to match them with investigational combination therapies that target specific genetic mutations. This approach aims to control tumor growth and improve …
This study investigates how effective one year versus two years of maintenance therapy is for patients with advanced ovarian cancer that has BRCA1/2 mutations or is homologous recombination deficient (HRD+). The purpose is to compare the effects of using the investigational medication, olaparib, with or without an antiangiogenic agent, bevacizumab, …
The purpose of this study is to investigate the effectiveness of an investigational medication in patients with HER2-positive solid tumors that are locally advanced, unresectable, or metastatic. In this study, HER2-positive is identified as IHC 3+. The study focuses on patients who have previously received systemic treatment for their condition …
The objective of this consortium is to generate and utilize omics level data to elucidate the early steps in ovarian cancer (OvCa) initiation and provide the broader OvCa research community with a centralized resource of comprehensive omics datasets surveying the molecular landscapes of OvCa precursor lesions and their associated microenvironment. …
This study investigates ovarian cancer. The purpose of this study is to compare the investigational medication, Sofetabart Mipitecan, with standard chemotherapy or other treatments for ovarian cancer.The study evaluates the effectiveness and safety of Sofetabart Mipitecan in treating ovarian cancer compared to current standard treatments.Who can participate: Participants must be …
This study investigates an investigational medication for women with advanced platinum-resistant epithelial ovarian cancer, including primary peritoneal and fallopian tube cancers. The purpose of this study is to evaluate the safety and effectiveness of the investigational medication in treating these types of cancers, which are known for being difficult to …
The purpose of this study is to assess the safety and effectiveness of a combination of investigational medication and another drug in treating advanced-stage ovarian, fallopian tube, or primary peritoneal cancer. This study targets cancers that express a specific protein called folate receptor alpha (FRα). This protein is found on …
Primary Objective 1. To explore genetic, proteomic, and molecular characteristics associated with recurrence less than six months following completion of frontline adjuvant combination platinum-based chemotherapy versus recurrence 18 months following completion of frontline adjuvant combination platinum-based chemotherapy. 2. To create a biorepository of tissue and blood that will be used …
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