Found 54 Allergy trials
A listing of Allergy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study aims to learn more about the use of Mirvetuximab soravtansine and Olaparib as a maintenance therapy after completion of prior therapy for recurrent platinum sensitive ovarian, peritoneal and fallopian tube cancer. Mirvetuximab soravtansine is an effective antibody drug conjugate that targets folate receptor alpha. Olaparib is one of …
This study investigates ovarian cancer. The purpose of this study is to compare the investigational medication, Sofetabart Mipitecan, with standard chemotherapy or other treatments for ovarian cancer.The study evaluates the effectiveness and safety of Sofetabart Mipitecan in treating ovarian cancer compared to current standard treatments.Who can participate: Participants must be …
The purpose of this study is to provide access to an investigational treatment for adult patients with acute lymphoblastic leukemia (ALL). This study is focused on patients who have already had a procedure called leukapheresis, where blood cells are collected, and have had an investigational treatment made from their cells, …
The NCI SHIP multi-site trial will recruit 100 individuals at Penn scheduled to undergo colposcopy to 1) evaluate self- and clinician-collected test primary HPV test accuracy by calculating clinical sensitivity and specificity for detection of CIN2+n histopathology; and 2) positive and negative percent agreement between self- and clinician-collected HPV samples.
This study investigates the use of a device to evaluate skin lesions that may suggest conditions like melanoma, basal cell carcinoma, and squamous cell carcinoma. The purpose of this study is to assess how accurately the device can identify these conditions in patients 22 years and older.Participants will have their …
This study investigates spinal and sacral chordoma. It focuses on the effects of neoadjuvant radiation therapy, including proton therapy and stereotactic body radiation therapy, on circulating tumor DNA (ctDNA) and imaging changes.The study evaluates if biomarkers can be used to understand changes after radiation therapy. It looks at ctDNA levels …
Glioblastoma (GBM) is the most common primary brain tumor in adults and is uniformly fatal. During standard adjuvant treatment for GBM following initial surgical resection of the tumor, patients are treated with a combination of radiation and chemotherapy. During and after this adjuvant treatment, patients are monitored for disease progression …
This study investigates the use of an investigational medication in patients with advanced solid tumors, specifically focusing on its effects as a single agent or in combination with other therapies. The purpose is to determine the recommended Phase II dose and to evaluate its safety, tolerability, and anti-tumor activity. The …
Determine interrater reliability between 3D whole body image assessment and in-person clinical assessment regarding the need for in-person evaluation of keratinocyte carcinomas in high-risk patients. VectraWB360 3D whole-body photography-based assessment by a dermatologist (Approach 1). In-person clinical assessment by a dermatologist (Approach 2). Determine interrater reliability between 3D whole body …
This study investigates the use of interstitial photodynamic therapy (I-PDT) following palliative radiotherapy in patients with inoperable malignant central airway obstruction. The purpose of this study is to test the safety and effectiveness of combining these treatments to improve tumor response and survival in patients whose airways are blocked by …
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