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Found 11 Head and Neck Cancer trials

A listing of Head and Neck Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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21 years or above
All genders
Phase 1
Interventional
This study investigates fibrotic conditions. It uses Fibroblast Activating Protein (FAP) PET/CT imaging to look at fibrosis caused by different medical conditions.The study evaluates if this imaging method can show how fibrosis affects major organs and tissues. It focuses on understanding the distribution of FAP in the body.Who can participate: …
18 years or above
All genders
Interventional
This study investigates the effectiveness of a self-management program for head and neck cancer survivors who experience lymphedema and fibrosis. The purpose of this study is to evaluate how well the self-management program can help manage these conditions and improve the quality of life for participants.Participants will be assigned to …
18 years or above
All genders
Interventional
This study investigates two different ways to manage lymphedema in individuals who have survived head and neck cancer. This study compares clinic-based Complete Decongestive Therapy (CDT) with a home-based hybrid model of CDT to see how each approach affects the severity of lymphedema in participants.Participants will either receive CDT in …
18 years or above
All genders
Interventional
This study investigates the effects of photobiomodulation therapy (PBMT) on chronic lymphedema in survivors of head and neck cancer. PBMT is a type of light therapy that has been approved by the U.S. Food and Drug Administration for treating arm lymphedema related to breast cancer. This study aims to confirm …
99 years or below
All genders
The aim of this cohort study to determine the oncologic and functional outcomes following all patients who underwent the transoral robotic surgery (TORS) in order to compare TORS to other surgical approaches.
18 years or above
All genders
Observational
This study investigates head and neck squamous cell carcinoma (HNSCC). The purpose of this study is to understand the molecular characteristics of HNSCC by profiling biomarkers in tissue and blood samples from patients undergoing their usual care treatment.Participants in this study will have their tissue and blood samples collected for …
18 years - 74 years
All genders
Phase 1
Interventional
This study investigates head and neck squamous cell carcinoma. The purpose of this study is to evaluate the safety and effectiveness of an investigational medication when used with standard chemotherapy and radiation therapy.The study focuses on assessing how well the investigational medication works with chemoradiation therapy. It evaluates the treatment's …
18 years or above
All genders
Phase 1/2
Interventional
This study investigates the use of an investigational medication in patients with advanced solid tumors, specifically focusing on its effects as a single agent or in combination with other therapies. The purpose is to determine the recommended Phase II dose and to evaluate its safety, tolerability, and anti-tumor activity. The …
18 years or above
All genders
Phase 1
Interventional
This study investigates the safety and effectiveness of an investigational medication in combination with immuno-oncology agents for individuals with advanced or metastatic solid tumors that cannot be surgically removed. The purpose of this study is to understand how the investigational medication, when used alone or with other treatments like nivolumab, …
12 years or above
All genders
Phase 1/2
Interventional
This study investigates the safety and effectiveness of an investigational medication in patients with locally advanced or metastatic solid tumors that have a specific mutation in the TP53 gene called Y220C. The study is divided into different phases to assess the medication alone and in combination with another treatment. The …
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