Found 8 Traumatic Brain Injury trials
A listing of Traumatic Brain Injury medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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We are researching whether sildenafil (or a placebo) can improve cerebrovascular reactivity (CVR) in the brain for individuals with ongoing symptoms from a brain injury. CVR is the brain's ability to adjust blood vessel size to maintain proper blood flow based on its oxygen needs. Sildenafil, commonly known as Viagra, …
This study investigates the changes in the brain that occur in the first three years following a traumatic brain injury (TBI). The purpose of this study is to compare the rate of brain tissue loss in individuals with TBI to those without, using healthy participants as a control group.Participants in …
The primary objective is to establish the merit and feasibility of QUTE-CE MRI vascular imaging biomarkers for detecting vascular abnormalities in (n=10) patients with TBI at least 6 months after injury compared to (n=10-16) healthy control (HC) subjects using IV Ferumoxytol as a contrast agent. The single timepoint visit includes: …
The goal of this study is to better understand that which contributes to the long-term recovery of people who have sustained a traumatic brain injury. To better understand an individual’s recovery following a head-injury, we will measure and examine the chemicals released in the brain and blood following the injury. …
TRACK-TBI EPI is an observational study of the TRACK-TBI longitudinal cohort. Subjects will be contacted 2-5 years after their index TBI for consent to a phone interview. Those who screen positive for possible post-traumatic epilepsy will be invited for an in person visit, which will involve a clinical evaluation by …
The objective of this study is to show that inhaled nitric oxide can increase blood flow in the brain after traumatic brain injury, attenuating brain injury and resulting in improved long-term function. We will use optical brain monitoring to determine changes in cerebral perfusion and metabolism by iNO treatment in …
The research study is being conducted to better understand brain metabolism, i.e. how the brain uses and consumes the various nutrients that are available in the blood. Changes in brain metabolism have been implicated in dementia and psychiatric disorders, as well as short- and long-term outcomes of traumatic brain injury …
This study investigates the use of bone marrow transplantation for patients newly diagnosed with severe aplastic anemia (SAA). The study aims to determine if patients with SAA can be effectively treated with a bone marrow transplant as their first therapy option, using donors who are either haploidentical related or unrelated, …
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