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Found 7 Traumatic Brain Injury trials

A listing of Traumatic Brain Injury medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

99 or below
All genders
To assess TMS-EEG abilities to aid in diagnosis, prognosis, and classification of TBI patients and predictions of clinical outcomes as well as to assess Delphi-MD abilities in the classification of TBI injury in comparison to standard brain measures. Differentiating between healthy controls and TBI participants in measured outputs of the …
 Phase 2 Randomized Controlled Trial of Sildenafil Citrate for Treatment of Cerebrovascular Dysfunction in Chronic Traumatic Brain Injury
18 - 70
All genders
Phase 2
We are researching whether sildenafil (or a placebo) can improve cerebrovascular reactivity (CVR) in the brain for individuals with ongoing symptoms from a brain injury. CVR is the brain's ability to adjust blood vessel size to maintain proper blood flow based on its oxygen needs. Sildenafil, commonly known as Viagra, …
 Transforming Research and Clinical Knowledge in Traumatic Brain Injury: Biomarker Project
18 - 99
All genders
The goal of this study is to better understand that which contributes to the long-term recovery of people who have sustained a traumatic brain injury. To better understand an individual’s recovery following a head-injury, we will measure and examine the chemicals released in the brain and blood following the injury. …
99 or below
All genders
To determine whether treatment guided by electrocorticographic monitoring of spreading depolarizations improves outcomes in patients who require surgery for severe TBI in the neuro intensive unit.
99 or below
All genders
See below. To characterize the patterns of longitudinal change in brain volume, white matter myelin content, and measures of NVU function (cerebral blood flow (CBF), CVR, BBB permeability, and extracellular free water) over the first 3 years following TBI. To determine the prognostic value of NVU measures (CBF, CVR, BBB …
 Brain Arterio-Venous Metabolomic Profiling
18 - 99
All genders
The research study is being conducted to better understand brain metabolism, i.e. how the brain uses and consumes the various nutrients that are available in the blood. Changes in brain metabolism have been implicated in dementia and psychiatric disorders, as well as short- and long-term outcomes of traumatic brain injury …
 Transforming Research and Clinical Knowledge in Traumatic Brain Injury Epileptogenesis Project
18 - 90
All genders
Observational
TRACK-TBI EPI is an observational study of the TRACK-TBI longitudinal cohort. Subjects will be contacted 2-5 years after their index TBI for consent to a phone interview. Those who screen positive for possible post-traumatic epilepsy will be invited for an in person visit, which will involve a clinical evaluation by …