Found 8 Traumatic Brain Injury trials
A listing of Traumatic Brain Injury medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
The overall objective of the study is to assess the safety and tolerability of MR-301 in improving rate of recovery in patients with severe non-penetrating Traumatic Brain Injury (TBI). The primary outcome variables are measurements of the frequency, severity, and type of drug-related adverse events and serious adverse events between …
To assess TMS-EEG abilities to aid in diagnosis, prognosis, and classification of TBI patients and predictions of clinical outcomes as well as to assess Delphi-MD abilities in the classification of TBI injury in comparison to standard brain measures. Differentiating between healthy controls and TBI participants in measured outputs of the …
We are researching whether sildenafil (or a placebo) can improve cerebrovascular reactivity (CVR) in the brain for individuals with ongoing symptoms from a brain injury. CVR is the brain's ability to adjust blood vessel size to maintain proper blood flow based on its oxygen needs. Sildenafil, commonly known as Viagra, …
The goal of this study is to better understand that which contributes to the long-term recovery of people who have sustained a traumatic brain injury. To better understand an individual’s recovery following a head-injury, we will measure and examine the chemicals released in the brain and blood following the injury. …
To determine whether treatment guided by electrocorticographic monitoring of spreading depolarizations improves outcomes in patients who require surgery for severe TBI in the neuro intensive unit.
See below. To characterize the patterns of longitudinal change in brain volume, white matter myelin content, and measures of NVU function (cerebral blood flow (CBF), CVR, BBB permeability, and extracellular free water) over the first 3 years following TBI. To determine the prognostic value of NVU measures (CBF, CVR, BBB …
The research study is being conducted to better understand brain metabolism, i.e. how the brain uses and consumes the various nutrients that are available in the blood. Changes in brain metabolism have been implicated in dementia and psychiatric disorders, as well as short- and long-term outcomes of traumatic brain injury …
TRACK-TBI EPI is an observational study of the TRACK-TBI longitudinal cohort. Subjects will be contacted 2-5 years after their index TBI for consent to a phone interview. Those who screen positive for possible post-traumatic epilepsy will be invited for an in person visit, which will involve a clinical evaluation by …
