Found 4 Scleroderma trials
A listing of Scleroderma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
The research study is being done to understand both why and how scleroderma and related female-biased diseases affect women and men differently. Though we do not know what causes these diseases, we do know that women are much more likely to develop them than men. We are studying how the …
Systemic sclerosis is a rare chronic autoimmune connective tissue disease. B cells have been reported to play a central role in the pathogenesis of SSc and B cell depletion has been shown to offer benefit to patients with SSc. Belimumab is a monoclonal antibody, which inhibits the survival of B …
Our goal is to identify markers which can predict response to therapy in patients with dermatomyositis, systemic sclerosis, lupus erythematosus, morphea, eosinophilic fasciitis, and other immune-mediated cutaneous and rheumatic diseases. To collect human tissue from lesional and non-lesional skin, as well as blood, cheek swabs, photographs of biopsy site(s) or …
The purpose of this study is to assess the safety, tolerability, and clinical activity of KYV-101 (a fully-human anti-CD19 CAR T-cell therapy) in adult subjects with B cell-driven autoimmune diseases. The diseases under study include: idiopathic necrotizing myopathy (INM) consisting of dermatomyositis (DM), necrotizing myopathy, anti-HMGCoA-associated myopathy, and polymyositis (PM), …
