Found 11 Parkinson's Disease trials
A listing of Parkinson's Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study aims to collect and share Parkinson’s disease genetic testing data from up to 500,000 study participants for research use. Participants will include people with Parkinson's disease (PD). To investigate the genetic link to PD, we will ask participants to contribute their genetic test results and associated raw data …
The study is designed to evaluate the efficacy and safety of intraputaminal delivery of AAV2-GDNF gene therapy in subjects with moderate Parkinson's disease and demonstrate proof-of-concept. Subjects will be randomized to 1 of 2 treatment arms, AAV2-GDNF surgery or control surgery and will undergo screening, two baseline visits, perioperative procedures, …
To characterize the neurophysiologic signatures of movement disorders symptoms in conditions such as Parkinson's disease, essential tremor, ataxia, and dystonia.
This study investigates the effects of an investigational medication compared to a placebo in individuals with Parkinson's disease.The study evaluates the safety, effectiveness, and how the body processes the investigational medication. It looks at participants who are already on a stable treatment.Who can participate: Adults with early-stage Parkinson's disease on …
The objective of this study is to obtain neural recordings to elucidate the neural mechanisms underlying food-cue processing in the subthalamic nucleus (STN) of patients with Parkinson's disease (PD) undergoing deep brain stimulation (DBS). By exploring these mechanisms, we aim to enhance our understanding of how DBS influences weight changes …
The objective of this study is to determine whether visual pathway structure and function correlates with hallucination severity and treatment outcomes in Parkinson disease. The primary outcome variable is hallucination severity, which will be quantified using the PD-adapted Scale for the Assessment of Positive Symptoms (SAPS-PD), a standardized semi-structured instrument …
This study investigates the presence of certain brain proteins in people with conditions like Progressive Supranuclear Palsy, Corticobasal Syndrome, genetic Frontotemporal Lobar Degeneration, Parkinson's Disease, Alzheimer's Disease, and healthy individuals. These conditions are collectively known as tauopathies.The study evaluates how a special substance, which can be seen in brain scans, …
BHV-8000 is a novel, brain-penetrant, selective dual inhibitor of Tyrosine Kinase 2 (TYK2) and Janus Kinase 1 (JAK1) that is being investigated as a treatment for early Parkinson's disease (PD).
This study investigates the use of an investigational medication to treat Adjustment Disorder (AjD) in patients with cancer and other medical conditions such as Amyotrophic Lateral Sclerosis (ALS), Multiple Sclerosis (MS), Parkinson's Disease (PD), or Idiopathic Pulmonary Fibrosis (IPF). The purpose of this study is to assess whether a single …
We are conducting research studies on how immune system cells contribute to inflammatory conditions of the nervous system, such as multiple sclerosis, neuromyelitis optica (NMO), encephalitis, head injury, epilepsy, Parkinson's disease (PD), Alzheimer's disease (AzD), Lou Gherig's disease (amyotrophic lateral sclerosis; ALS) frontotemporal dementia (FTD) and others. This includes investigating …
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