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Found 13 Parkinson's Disease trials

A listing of Parkinson's Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 A Open-Label Ascending Dose Study to Evaluate the Safety and Effects of PR001A in Patients With Parkinson's Disease

A Open-Label Ascending Dose Study to Evaluate the Safety and Effects of PR001A in Patients With Parkinson's Disease

35-80 years
All genders
Phase 1
Interventional
This is a 5 year study and the purpose is to assess the safety and tolerability of 2 dose levels of PR001A administered via l injection in patients with moderate to severe Parkinson's Disease

Parkinsons Foundation PD GENEration Genetic Registry

18-99 years
All genders
Observational
This study aims to collect and share Parkinson’s disease genetic testing data from up to 500,000 study participants for research use. Participants will include people with Parkinson's disease (PD). To investigate the genetic link to PD, we will ask participants to contribute their genetic test results and associated raw data …
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Online study

Study to Determine the Efficacy and Safety of BIIB122 in Participants with Parkinsons Disease

30-80 years
All genders
The LRRK2protein may contribute to disease progression in patients with PD.The study drug (BIIB122) is designed to affect the activity of LRRK2 protein in the brain and may prevent or delay the development of PD symptoms.The main purpose of this study is to look at whether the study drug works …

A Study of AAV2-GDNF in Adults with Moderate Parkinsons Disease (REGENERATE-PD)

99 years and younger
All genders
Phase 2
The study is designed to evaluate the efficacy and safety of intraputaminal delivery of AAV2-GDNF gene therapy in subjects with moderate Parkinson's disease and demonstrate proof-of-concept. Subjects will be randomized to 1 of 2 treatment arms, AAV2-GDNF surgery or control surgery and will undergo screening, two baseline visits, perioperative procedures, …

An extension study to evaluate the long-term efficacy and safety of minzasolmin (UCB0599) in study participants with Parkinsons disease

99 years and younger
All genders
Subjects currently enrolled in the PD0053 can be enrolled in this study. Subjects will take UCB0599 capsules twice a day at either 180 mg or 360 mg approximately 12 hours apart. The start of the study will overlap with the end of the parent study and run for 30 months …

PD DBS Sleep Study

99 years and younger
All genders
The purpose of this study is to gain a better understanding of how signals in the brain contribute to abnormal sleep behavior in patients with Parkinson's Disease (PD).

M20-098

99 years and younger
All genders
PURPOSE This is an extension of the M15-736 study to assess the long-term safety, tolerability and efficacy of ABBV-951 delivered as a CSCI for 24 hours daily at personally optimized therapeutic doses in patients with Parkinson's Disease.

STEM-PD

99 years and younger
All genders
Non-Invasive Brainstem Modulation for the Treatment of Non-Motor Symptoms in Parkinsons Disease: A Randomized Controlled Trial (RCT) and an Open Label Extension (OLE) Study
 The Parkinsons Progression Markers Initiative (PPMI) 2.0 Clinical - Establishing a Deeply Phenotyped PD Cohort

The Parkinsons Progression Markers Initiative (PPMI) 2.0 Clinical - Establishing a Deeply Phenotyped PD Cohort

18-99 years
Healthy Volunteer
All genders
The purpose of this study is to continue to obtain information from people with and without Parkinson disease (PD) so that researchers may better understand how Parkinson disease progresses, in order to inform better treatments. The information collected in this study is for research and not for clinical care. This …

Racial Disparities in PD

99 years and younger
All genders
The purpose of this study is to look at racial disparities in people with Parkinsons Disease (PD) by studying symptoms and signs, management, and genes in Black PD patients compared to a group of White PD patients.
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