Found 10 Parkinson's Disease trials
A listing of Parkinson's Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
This is a 5 year study and the purpose is to assess the safety and tolerability of 2 dose levels of PR001A administered via l injection in patients with moderate to severe Parkinson's Disease
This study aims to collect and share Parkinson’s disease genetic testing data from up to 500,000 study participants for research use. Participants will include people with Parkinson's disease (PD). To investigate the genetic link to PD, we will ask participants to contribute their genetic test results and associated raw data …
The LRRK2protein may contribute to disease progression in patients with PD.The study drug (BIIB122) is designed to affect the activity of LRRK2 protein in the brain and may prevent or delay the development of PD symptoms.The main purpose of this study is to look at whether the study drug works …
The study is designed to evaluate the efficacy and safety of intraputaminal delivery of AAV2-GDNF gene therapy in subjects with moderate Parkinson's disease and demonstrate proof-of-concept. Subjects will be randomized to 1 of 2 treatment arms, AAV2-GDNF surgery or control surgery and will undergo screening, two baseline visits, perioperative procedures, …
The purpose of this study is to look at racial disparities in people with Parkinsons Disease (PD) by studying symptoms and signs, management, and genes in Black PD patients compared to a group of White PD patients.
Subjects currently enrolled in the PD0053 can be enrolled in this study. Subjects will take UCB0599 capsules twice a day at either 180 mg or 360 mg approximately 12 hours apart. The start of the study will overlap with the end of the parent study and run for 30 months …
The purpose of this study is to gain a better understanding of how signals in the brain contribute to abnormal sleep behavior in patients with Parkinson's Disease (PD).
We are conducting research studies on how immune system cells contribute to inflammatory conditions of the nervous system, such as multiple sclerosis, neuromyelitis optica (NMO), encephalitis, head injury, epilepsy, Parkinson's disease (PD), Alzheimer's disease (AzD), Lou Gherig's disease (amyotrophic lateral sclerosis; ALS) frontotemporal dementia (FTD) and others. This includes investigating …
The objective of this study is to determine whether visual pathway structure and function correlates with hallucination severity and treatment outcomes in Parkinson disease. The primary outcome variable is hallucination severity, which will be quantified using the PD-adapted Scale for the Assessment of Positive Symptoms (SAPS-PD), a standardized semi-structured instrument …
The primary objective is to test whether the progression of the signs of Parkinson's disease is attenuated at 12 months in among persons who have not initiated medication for Parkinson Disease (PD) when they perform high-intensity endurance treadmill exercise.
