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Found 13 Pancreatic Disorders trials

A listing of Pancreatic Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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UPCC 17925/28925 Molecular Residual Disease in Solid Tumors: A Prospective Study to Collect Clinical Data and Biospecimens to Support Discovery and Development of Cancer Biomarkers
18 years or above
All genders
Observational
This study investigates solid tumors. Participants will provide clinical data and biological samples to support cancer biomarker research.The focus of this study is to evaluate the development of tests for cancer detection and assessing the risk of cancer recurrence.Who can participate: Adults aged 18 and older with a confirmed diagnosis …
Effect of GLP-1 Agonist Therapy on Insulin Secretion in Adults with Pancreatic Insufficient Cystic Fibrosis and Abnormal Glucose Tolerance: a randomized  open-label  cross-over trial
18 years - 50 years
All genders
The research study is being conducted to better understand Cystic-Fibrosis Related Diabetes (CFRD) and to see the effects of an analog of the gut incretin hormone, GLP-1 (dulaglutide), has on individuals like with abnormal glucose tolerance. GLP-1 (dulaglutide) helps the pancreas release insulin, which controls blood sugar levels from getting …
A Phase 1/2 Study to Evaluate the Safety, Tolerability, and Efficacy of VX-880 in Subjects Who Have Type 1 Diabetes Mellitus with Impaired Hypoglycemic Awareness and Severe Hypoglycemia
18 years - 65 years
All genders
Phase 1/2
Interventional
In T1D the body’s immune system destroys insulin producing cells called beta cells. This meansthe body cannot produce enough insulin to control the amount of sugar in the blood. Beta cellsare located in the pancreas and are part of clusters of cells called pancreatic islets.These cells produce hormones such as …
18 years or above
All genders
Observational
The purpose of this study is to investigate potential markers of pancreatic cancer found in the blood. By collecting blood samples from participants, researchers aim to link these markers to medical and health information. This study may provide insights into detecting pancreatic cancer in the blood before other methods can, …
UPCC 30213 The Cancer of the Pancreas Screening-5
18 years or above
All genders
Phase 3
Interventional
This study investigates screening methods for pancreatic cancer in individuals who are at high risk due to genetic factors or family history. The purpose of this study is to better understand the effectiveness of these screening methods in detecting early signs of pancreatic cancer.Participants in this study will undergo procedures …
50 years - 75 years
All genders
Observational
This study investigates different methods for monitoring pancreatic cysts. Monitoring these cysts is important to prevent complications. The purpose of this study is to compare two approaches: more frequent monitoring versus less frequent monitoring, to see which one leads to better outcomes for patients with pancreatic cysts.Participants in the study …
EA2192 APOLLO: A Randomized Phase II Double-Blind Study of Olaparib versus Placebo Following Curative Intent Therapy in Patients with Resected Pancreatic Cancer and a Pathogenic BRCA1, BRCA2 or PALB2 Mutation
18 years or above
All genders
Phase 2
Interventional
This study investigates the effectiveness of an investigational medication following surgery and chemotherapy in patients with pancreatic cancer who have specific genetic mutations. The study focuses on patients whose cancer has been surgically removed and who have a mutation in the BRCA1, BRCA2, or PALB2 genes. These genes are known …
18 years or above
All genders
Phase 1
Interventional
This study investigates the treatment of KRAS-mutated cancers. The purpose of this study is to evaluate the safety and preliminary effectiveness of a new investigational treatment in patients with specific types of cancer that have a KRAS mutation.The study focuses on assessing the safety and how well the investigational treatment …
18 years or above
All genders
Observational
This study investigates circulating biomarkers in patients with pancreatic adenocarcinoma. The purpose of this study is to collect blood samples from patients to evaluate these biomarkers, which are substances that can be measured in the blood and may provide information about the cancer.Participants will undergo a procedure to collect blood …
18 years or above
All genders
Phase 1/2
Interventional
This study investigates the safety and clinical activity of an investigational medication in participants with advanced solid tumors that have a specific genetic mutation known as KRAS G12C. The purpose of this study is to evaluate how the investigational medication works in different phases, including dose escalation and expansion, to …
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