Found 12 Nephropathy trials
A listing of Nephropathy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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Type 2 diabetes is the most common cause of chronic kidney disease (CKD). In people with diabetes, the kidneys do not function normally and continuously require more oxygen to remove waste from the body. This process, in-turn, depletes the available supply of oxygen, causes damage to the tissue itself, and …
The purpose of the study is to determine the changes in muscle metabolites by MRI before and after exercise. The MRI will be performed while performing mild exercise of the calf muscle for 1-3 minutes. We are actively recruiting adults between 45-55 and 70-84. Volunteers cannot have diabetes, liver disease, kidney …
The purpose of this study is to investigate ADPKD, focusing on the PKD1/2 gene variants. The study looks at how common these gene variants are and the characteristics of people who have them.This study evaluates the different traits and demographics of individuals with these gene variants. It explores the clinical …
This research study is being done to learn about the effects of the study drug, Atacicept, on reducing damage to the kidneys and to see how safe the study drug is for people with IgA nephropathy (IgAN), IgA vasculitis with nephritis (IgAVN), primary membranous nephropathy (pMN), minimal change disease (MCD), …
MZE829-201 is a Phase 2, open-label study of MZE829 in adults aged 18 to 65 years with proteinuric chronic kidney disease (CKD) and the APOL1 high risk genotype, or APOL1 Kidney Disease (AKD). It aims to evaluate the safety and tolerability of MZE829 in adults with proteinuric AKD, to evaluate …
This study examines the safety, tolerability, and effectiveness of AZD2373 in APOL1-Mediated Kidney Disease (AMKD). Some people have a variant in the APOL1 gene that is associated with protection against African sleeping sickness but increases the risk of kidney disease in some people. There is currently no approved treatment for …
This study investigates myocardial glucose suppression in FDG PET/CT scans. The purpose of this study is to evaluate the effect of sodium-glucose cotransporter-1/2 inhibitors on glucose levels in the heart.The study evaluates the safety and effectiveness of combining a ketogenic diet with an investigational medication to enhance imaging results. Researchers …
This is a Phase 3b, multicenter, open-label extension (OLE) study to evaluate the efficacy and safety of Nefecon treatment in patients with IgAN who have completed the Phase 3 Study Nef 301 and continue to be treated with a stable dose of RAS inhibitor therapy (ACEIs and/or ARBs). Patients who …
The research study is being conducted to test how providing trauma-informed care training to health care providers and support from a community health worker to patients may affect health outcomes for people with lower kidney functioning, also known as “chronic kidney disease.” Chronic kidney disease can be caused by health …
HOPE is a randomized clinical trial that will evaluate approaches to reducing pain and opioid use among patients with chronic pain who are receiving maintenance hemodialysis for end-stage renal disease. The hypothesis is that pain coping skills training will be effective at reducing pain and opioid use, and that buprenorphine …
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