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Found 8 ob-gynecologic-oncology trials

A listing of ob-gynecologic-oncology medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

18 years and older
All genders
Phase 1
The study will evaluate the safety profile of escalating doses of continuous daily oral ATRN-119 and to determine the maximum tolerated dose (MTD) and recommended dose. ATRN-119 is a drug that has been developed to treat cancers by taking advantage of genetic mutations found only in the tumor and not …
18-100 years
Female
Phase 1/2
This study is divided into 2 parts (Escalation and Expansion).  Your study doctor or study staff will also let you know you in what part of the study you will participate.The purpose of Part 1 (Escalation) of the study is to find the highest, safe dose of the study drug(s), …
Female
Phase 3
This phase III trial studies how well letrozole with or without paclitaxel and carboplatin works in treating patients with stage II-IV low-grade serous carcinoma of the ovary, fallopian tube, or peritoneum. Letrozole is an enzyme inhibitor that lowers the amount of estrogen made by the body which in turn may …
18-99 years
All genders
Phase 1
Interventional
This study involves research of an investigational therapy called SynKIR-110. SynKIR-110 is CAR T cell therapy. CAR T cell therapy is a type of treatment in which a patient’s T cells (white blood cells that are a part of the immune system) are changed in a laboratory so they can …
Female
Phase 1
NP-G2-044 Monotherapy Primary Objectives The primary objectives for patients receiving NP-G2-044 monotherapy are the following: 1) to identify the recommended Phase 2 dose (RP2D) of continuously dosed NP-G2-044 monotherapy (Mono-RP2D) and characterize its safety; and 2) to assess preliminary signals of NP-G2-044 anti-tumor efficacy when administered as continuously dosed monotherapy. 
18 years and older
All genders
Phase 2
The purpose of the study is to assess whether an investigational drug, called XmAb20717, has any effects on certain types of cancers and if it is safe and well tolerated.
 NRG-CC008: A study to compare two surgical procedures in women with BRCA1 mutations to assess reduced risk of ovarian cancer
50 years and younger
Female
This clinical trial studies how well two surgical procedures (bilateral salpingectomy and bilateral salpingo-oophorectomy) work in reducing the risk of ovarian cancer for individuals with BRCA1 mutations. Bilateral salpingectomy involves the surgical removal of fallopian tubes, and bilateral salpingo-oophorectomy involves the surgical removal of both the fallopian tubes and ovaries. …
 Zn-c3-005: A Phase 2 Open-Label, Multicenter Study to Evaluate Efficacy and Safety of ZN-c3 Subjects With High-Grade Serous Ovarian, Fallopian Tube, Or Primary Peritoneal Cancer
100 years and younger
Female
Phase 2
A Phase 2 study to evaluate the clinical activity, safety, and potentially predictive biomarker profile of ZN-c3 in subjects with High-Grade Serous Ovarian, Fallopian Tube, or Primary Peritoneal Cancer