Found 25 dm-cardiology-waxman trials
A listing of dm-cardiology-waxman medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This is a global, multicenter, prospective, observational study designed to document clinical characteristics and treatment patterns of adult patients with ATTR-CM treated with vutrisiran or other approved ATTR-CM treatments and to evaluate long-term effectiveness of vutrisiran compared to other approved ATTR-CM treatments. Data will be collected retrospectively and prospectively from …
This is an interventional, randomised, multinational, multicentre, two arm parallel-group, double-blind study. The aim of this study is to evaluate the effect of NNC6019-0001 4800 mg versus placebo in participants with variant or wild-type transthyretin (TTR) amyloid cardiomyopathy (ATTRv-CM or ATTRwt-CM, respectively)
This is a prospective, multi-center, randomized, indication expansion investigational device exemption study. This study will look at the safety and effectiveness of left bundle branch area pacing (LBBAP) in patients with heart failure with reduced ejection fraction (HFrEF) and left bundle branch block (LBBB) with an indication for a cardiac …
The purpose of this study is to evaluate the efficacy and safety of concomitant use of eplontersen and ALXN2220 compared with eplontersen and placebo in adult participants with ATTR-CM who are treated with standard-of-care therapy as determined by the treating and study physician(s). The study duration will be up to …
Study AG10-404 is a single-arm, prospective, longitudinal, open-label study to investigate the long-term effects of acoramidis on improving cardiac function and structure, and on cardiac amyloid burden in participants with transthyretin amyloid cardiomyopathy (ATTR-CM) over 36 months using two well-established, complementary imaging modalities - cardiac echocardiography and cardiac magnetic resonance …
Open-label, multi-center, international, prospective, single-arm, study to obtain market approval for the LivIQ system. Patients with a class I or II indication for ventricular pacing (VVI/VDD), Bradycardia (slow heart rate) will be enrolled in the study. LivIQ VR-T DX is a leadless pacemaker, is an investigational device that can sense …
The study is a prospective, randomized, controlled, multi-center, premarket study in patients with Persistent Atrial Fibrillation (PsAF) undergoing first-time catheter ablation with the VARIPULSE Catheter System. Participants in the study will be randomized into one of two arms: Arm 1: PVI and SVCI Arm 2: PVI and SVCI + PWI …
This is a prospective global multicenter long-term observational study designed to document the clinical outcomes of patients with hereditary transthyretin-mediated amyloidosis or wild-type transthyretin-mediated amyloidosis and the safety of patisiran (Onpattro) when used in patients with ATTRv amyloidosis. This is data collection study only and no study medication no visits …
This open-label study is designed to evaluate the long-term safety and tolerability of acoramidis in participants with ATTR-CM, administered on a background of stable heart failure therapy. This study follows the randomized, double-blind, placebo-controlled Study AG10-301 which was designed to examine safety and efficacy in this same population.
This registry is a retrospective observational, multi-center study designed to collect data and analyze data retrospectively on patients with AL or TTR cardiac amyloidosis. Subjects under the care of the local investigator will be identified and consented. No patient visits or patient procedures will be required for the purpose of …
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