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Found 37 dm-pulmonary-allergy-and-critical-care trials

A listing of dm-pulmonary-allergy-and-critical-care medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

FROSTBITE-2

99 years and younger
All genders
See protocol section 2.1 See protocol section 2.2 See protocol section 2.3
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CMTX-101

99 years and younger
All genders
Determine safety and tolerability of IV administered doses of CMTX-101. Determine safety and tolerability of IV administered doses of CMTX-101. Assess the PK of different doses of CMTX-101. Evaluate immunogenicity (i.e., development of anti-drug antibodies [ADA] and neutralizing antibodies [Nabs]) of a single IV administered dose of CMTX-101. Assess the …
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Aerify III

99 years and younger
All genders
This study is an exploratory, two-part, 12-week, Phase 2a study to evaluate the mechanism of action of itepekimab (anti-IL-33-mAb) and its impact on airway inflammation in former and current smokers with COPD.
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1305-0031

99 years and younger
All genders
This is an OLE for all subjects we currently have enrolled in BI 1305-0014 and 1305-0023. Subjects will be on either 9 mg or 18 mg of IP based on results from the current studies. Procedures involve safety labs, lung function testing, clinical labs, ECGs, PEs, AE collection.
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Radiomics Tool for Pulmonary Nodule Risk Stratification

99 years and younger
All genders
The objective of this pragmatic clinical trial is to determine the real-world effect of a radiomics-based computer-aided diagnosis tool on pulmonary nodule management decisions. We hypothesize that a higher proportion of pulmonary nodules will be appropriately managed when clinicians prospectively use a CAD-based risk stratification strategy to evaluate pulmonary nodules. …
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CONVERT-II

99 years and younger
All genders
This is a prospective, open-label, multi-center, single-arm study enrolling subjects with severe heterogeneous emphysema and collateral ventilation in the target lobe. Subjects will undergo instillation of AeriSeal Foam in the target lobe and subsequent assessment CV status using Chartis Pulmonary Assessment System. Subjects with CV- status will then undergo placement …
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MUSCLE UP-PH

99 years and younger
All genders
PURPOSE This study will aim to (1) understand the way in which muscle loss occurs in Pulmonary Arterial Hypertension, particularly the role of fat surrounding the heart, and (2) look at the impact muscle loss has on quality of life, daily physical activity, and hospitalizations in patients with PAH. Subjects …
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PREVENT

99 years and younger
All genders
A Reliance Agreement with Beth Israel Deaconess Medical Center is requested (SMART IRB). Improved mechanical ventilation treatment strategies are needed to improve outcomes in ICU patients with acute respiratory distress syndrome (ARDS). This study compares standard mechanical ventilation to a lung-stress oriented ventilation strategy in patients with ARDS. Personalized, precision …
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PROSERA:

99 years and younger
All genders
Phase 3 study to evaluate the efficacy and safety of oral inhalation GB002 seralutinib for the treatment of pulmonary arterial hypertension (PAH). GB002 is a powder taken by inhalation twice a day. The drug is absorbed into the lungs. GB002 will be inhaled using an approved, hand-held device called a …
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REACH-OB-23

99 years and younger
All genders
This study is an observational study to collect data on individuals with CF who are not on modulators. Data will be collected on lab tests, microbiology results, lung function tests,questionnaires, antibiotic use,
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