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Found 28 dm-pulmonary-allergy-and-critical-care trials

A listing of dm-pulmonary-allergy-and-critical-care medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 Cooling to Help Injured lungs (CHILL) for  Therapeutic Hypothermia in Patients with ARDS (acute respiratory distress syndrome )
18 - 65
All genders
Phase 2
This study will analyze the potential lung protective effect of mild therapeutic hypothermia (TH), similar to that used for cardiac arrest, in ICU patients with acute respiratory distress syndrome (ARDS).
99 or below
All genders
To assess the effect of nintedanib on preserving L-PF measured symptom levels (cough, dyspnea, energy), impacts of disease, and quality of life in patients with MA-ILD who are also receiving SOC treatment.
40 - 80
All genders
This is a prospective, open-label, multi-center, single-arm study enrolling subjects with severe heterogeneous emphysema and collateral ventilation in the target lobe. Subjects will undergo instillation of AeriSeal Foam in the target lobe and subsequent assessment CV status using Chartis Pulmonary Assessment System. Subjects with CV- status will then undergo placement …
18 - 99
All genders
A Phase 2, randomized, open-label, active-controlled study of JNJ-90301900 in combination with chemoradiation followed by durvalumab in locally advanced and unresectable Stage III non-small cell lung cancer.
99 or below
All genders
Aim 1. Leverage existing biobanked oral, gut, respiratory tract and blood specimens of generally healthy adults for immediate initiation and scale-up of cross-sectional and archived longitudinal sample virome characterization.Aim 2. Access and re-enroll participants from previously-established cohorts, including those linked to the existing biobanks, for prospective virome sample collection and …
 Effect of study drug IL-4RR576 polymorphism on response to dupilumab in asthma
18 - 99
All genders
Phase 4
The purpose of this study is to learn if the study drug (Dupixent® Dupilumab) helps to control asthma. We are particularly interested in understanding if people who have a certain genetic make-up (genotype) will respond better to this treatment. Participants will take inhaler (Dulera®mometasone/formoterol) about 2-12 weeks. Total study duration …
 Assessment of Chronic Lung Allograft Dysfunction Using Single-Breath & Multi-Breath Hyperpolarized Xenon 129 MRI
18 - 90
All genders
We are investigating if using a special type of non-radiation imaging (inhaled hyperpolarized xenon with MRI) in lung transplant recipients can outperform current standard tests for transplant rejection. Presently, clinical assessments such as pulmonary function testing (PFT) are able to detect rejection of the transplanted lungs, however, they can only …
 ASPEN- A Phase 3  Randomized  Double-Blind  Placebo-Controlled Study to Assess the Efficacy  Safety  and Tolerability of Brensocatib Administered Once Daily for 52 Weeks in Subjects With Non-Cystic Fibrosis Bronchiectasis
18 - 85
All genders
Phase 3
Interventional
Penn Medicine patients already participating in protocol INS1007 301 will be invited to participate in this study. The Pharmacokinetic (PK) portion of this substudy is designed to evaluate the amount of brensocatib present in your blood at certain time periods before and after the study drug is administered, and the …
 ARISE - Study to Validate Patient-Reported Outcome Instruments in Adult Subjects with Newly Diagnosed Nontuberculous Mycobacterial (NTM) Lung Infection Caused by Mycobacterium avium Complex (MAC)
18 - 99
All genders
Phase 3
The purpose is to validate patient-reported outcomes questionnaire subjects given ALIS (amikacin liposome inhalation suspension) as part of a study treatment regimen for NontuberculousMycobacterial (NTM) Lung Infection. It will also evaluate the safety and efficacy of the study treatments with ALIS, azithromycin, and ethambutol. Targeted population is patients newly diagnosed …
 ENCORE - Study to Evaluate Amikacin Liposome Inhalation Suspension (ALIS)-Based Regimen in Adult Subjects with Newly Diagnosed Nontuberculous Mycobacterial (NTM) Lung Infection Caused by Mycobacterium avium Complex (MAC)
18 - 99
All genders
Phase 3
The purpose of this study is to evaluate the effect and safety of amikacin liposome inhalation suspension (ALIS) study treatment on patient-reported symptoms in subjects newly diagnosed with NTM lung infection caused by MAC who have not started standard treatment. This is an experimental clinical research study, and ALIS is …
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