A listing of ob-obstetrics-and-gynecology medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
This study will compare two treatments for Stress Urinary Incontinence, transurethral bulking agent (TBA) and single-incision sling (SIS). Patients unresponsive to conservative treatments, interested in minimally invasive surgical treatment will be asked to take part in this study. The purpose of this research is to help doctors determine the best …
This is a randomized, open-label, global Phase 3 study designed to assess the effect of sacituzumab govitecan (SG) compared with TPC (doxorubicin or paclitaxel) in participants with recurrent/persistent endometrial cancer who have received prior treatment with platinum-based chemotherapy and anti-programmed cell death protein 1/programmed cell death ligand 1 (anti-PD-1/PD-L1) therapy. …
This phase III trial studies how well letrozole with or without paclitaxel and carboplatin works in treating patients with stage II-IV low-grade serous carcinoma of the ovary, fallopian tube, or peritoneum. Letrozole is an enzyme inhibitor that lowers the amount of estrogen made by the body which in turn may …
The purpose of this study is to investigate if minimally invasive surgery, called robotic assisted laparoscopy (small incision surgery), is better or worse than open surgery (otherwise known as a laparotomy) when performing a radical hysterectomy for cervical cancer. A radical hysterectomy is surgery to remove the uterus, cervix, the …
The goal of this study is to better understand the genetic causes of non-immune hydrops fetalis (NIHF) and other types of abnormal fluid collections with genomic sequencing, detailed review of clinical information, and in some cases, additional research testing. As NIHF and other types of abnormal fluid collections are often …
This is a long-term follow up of participants enrolled in the CHAP trial during a 5-year window starting between 0-6 years until 5-10 years after their participation in the original CHAP trial. The goal is to determine whether treatment of mild CHTN in pregnancy influences maternal risk of cardiovascular disease …
The purpose of the study is to compare risk reducing salpingectomy with delayed oophorectomy to risk-reducing salpingo-oophorectomy in high risk-women.
Objective 1: Estimate efficacy of medical management with oral letrozole 10 mg daily for three consecutive days followed by vaginal misoprostol 800 mcg for treatment of EPL Objective 2: Assess side effects, adverse events, and patient acceptability associated with letrozole and misoprostol for medical management of EPL Our primary outcome …
To provide evidence for the safety and effectiveness of the May Health System in transvaginal ablation of ovarian tissue under transvaginal ultrasound guidance to restore ovulation in women with infertility due to polycystic ovary syndrome (PCOS) who have not responded to first-line ovulation induction treatment or are contraindicated for or …
The MoVEonUp Study is a NIH-funded study for women who are 70 years or older and experience urinary incontinence (bladder leaks). The study will test an exercise and bladder training program to reduce the risk of falling and improve bladder symptoms. No travel for the study is required. Study visits …