Found 11 thoracic trials
A listing of thoracic medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Changes in the Lymphatic System on the MR Lymphangiography (MRL) In Patients with Liver Cirrhosis
Phase 1
This is an observational study that will compare the differences in lymphatic flow and anatomy of the central lymphatic system on MRL in the liver cirrhosis patients with and without ascites. In the second part of the study, MRL anatomical and flow changes in the central lymphatic system of patients …
DISSECT-N is an Observational Registry to Assess Real-world Safety and Effectiveness of the Valiant Navion Thoracic Stent Graft in Routine Clinical Practice in Subjects Diagnosed With a Dissection of the Thoracic Aorta
This is a prospective, observational, global, multi-center, post-market registry intended to assess the real-world safety and effectiveness of the Valiant Navion Stent Graft System in the treatment of thoracic aortic dissections. The primary objective is composite safety and effectiveness at 1-month post-procedure.
A Prospective Observational Study of Outcomes from Proximal Thoracic Aortic Disease
The purpose of this registry is to collect real-time data for those patients who have aortic disease of their ascending (top) aorta and the aortic arch (curved area where the vessels that supply the brain with blood). The current treatment requires open surgery or a hybrid procedure (open surgery with …
Analysis of lymphatic fluid from the thoracic duct of healthy subjects and patients with MS before and during Ofatumumab treatment
The overall objectives of this study are to evaluate feasibility and safety of thoracic duct sampling, including "in-and-out" cannulation and "indwelling" catheterization in early MS and to compare cellular and signaling markers in thoracic duct lymph compared to measures in the blood, within and across populations of MS patients before …
External Drainage of Thoracic Duct Lymph to Reduce Inflammatory Cytokines in Septic Shock Patients: A Pilot Trial with Concurrent Controls to Confirm Safety and Assess Preliminary Efficacy
This is an interventional cohort study (n=10) that will involve external drainage of thoracic duct lymph in Surgical ICU patients with septic shock. The lymph drainage will continue for up to a maximum of 7 days and will be continued in those patients discharged from ICU back to the ward …
PILOT STUDY TO ASSESS LUNG FUNCTION USING PERFUSION BLOOD VOLUME DUAL ENERGY CT AND 4DCT DERIVED LUNG VENTILATION IMAGING
The basic premise of this pilot study is to enroll 40 patients over 1.5 years who have Stage III or IV non-small cell lung cancer and are planned for definitive treatment with concurrent chemoradiation when a contrast-enhanced 4DCT is planned. The primary goal is to quantify the reproducibility of lung …
Treatment In Thoracic Aortic Aneurysm: Surgery versus Surveillance
This study aims to compare the outcomes of patients undergoing early surgical intervention for ascending aortic aneurysms to those undergoing aneurysm surveillance. Patients with aneurysm diameters between 5.0 and 5.4 cm will be randomized to receive either medical therapy or elective surgery and will be followed annually for 5 years. …
Evaluation of the GORE TAG Thoracic Branch Endoprosthesis (TBE Device) in the Treatment of Lesions of the Aortic Arch and Descending Thoracic Aorta
The purpose of this study is to evaluate the safety and effectiveness of the study device, which is an endoprosthesis (stent) that is used to treat various lesions of the aortic arch and descending thoracic aorta. Lesions might include aortic aneurysm (weakened area of the aorta), dissection (tear in the …
Immunologic Analysis of Thoracic Duct Lymph from MS Patients and Controls
This study aims to investigate the benefits of collecting lymph in addition to blood in patients with multiple sclerosis (MS). It is now well recognized that the central nervous system (CNS) is not as immune privileged as it has been considered. A system of lymphatic drainage has been described both …
NHLBI Study
Establish a scalable reference library of anatomical 3D maps of the thoracic duct in healthy individuals Map lymphatic vessel 3D molecular maps of the tissue sample obtained during thoracic duct-venous re-anastomosis surgery to 3D cross-sectional (MR and/or CT) imaging of the region of interest 3. Coordinate with the HuBMAP Consortium …
1 - 10 of 11
- 1
- 2
