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Found 11 dm-rheumatology trials

A listing of dm-rheumatology medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 XCI Maintenance in Scleroderma and Related Female-Biased Diseases
35 - 90
All genders
The research study is being done to understand both why and how scleroderma and related female-biased diseases affect women and men differently.  Though we do not know what causes these diseases, we do know that women are much more likely to develop them than men.  We are studying how the …
 Study to Evaluate Nipocalimab in Participants with Active Idiopathic Inflammatory Myopathies
18 - 90
All genders
Phase 2
Interventional
The purpose of this study is to see if the investigational drug nipocalimab is safe and useful for treating patients with active Idiopathic Inflammatory Myopathies (IIM).  Another purpose is to find out if nipocalimab can cause side effects, which are unexpected or unwanted reactions from taking a drug.   An …
 Depemokimab compared with mepolizumab for relapsing or refractory EGPA on standard of care therapy
18 - 90
All genders
Phase 3
The purpose of this study is to learn more about eosinophilic granulomatosis with polyangiitis (EGPA) that returns (relapse) or has not responded to treatment, and if the investigational drug depemokimab can improve the disease.  This study is being done to help determine if depemokimab is safe and how it works …
99 or below
All genders
Phase 3
Systemic sclerosis is a rare chronic autoimmune connective tissue disease. B cells have been reported to play a central role in the pathogenesis of SSc and B cell depletion has been shown to offer benefit to patients with SSc. Belimumab is a monoclonal antibody, which inhibits the survival of B …
 Study to Investigate the Efficacy and Safety of NS-229 in the Treatment of EGPA
18 - 90
All genders
Phase 2
The main purpose of this study is to learn how well the investigational drug NS-229 works and how safe NS-229 is compared with placebo.  An investigational drug is one that is not approved by the United States Food and Drug Administration (FDA) to treat EGPA.   Participants could be in the …
99 or below
All genders
The primary objective of our proposed trial will be to test the hypothesis that a prolonged, unresolved skin inflammation coupled with musculoskeletal power-doppler ultrasound (MSKPDUS) abnormalities driven by IL-23 increase the risk for transition into PsA and that an intervention that targets one of these pivotal molecules (i.e., Guselkumab) will: …
99 or below
All genders
The purpose of this study is to better understand molecular pathways and joint destruction in patients with autoimmune diseases such as Psoriatic Arthritis (PsA).
99 or below
All genders
Request to rely on New England Institutional Review Board Request to rely on New England Institutional Review Board Request to rely on New England Institutional Review Board
99 or below
All genders
Please see Protocol Section 3 Please see Protocol Section 3 Please see Protocol Section 3
18 - 90
All genders
Phase 2
The purpose of this study is to see whether a drug called naltrexone improves health-related quality of life in patients with vasculitis. Naltrexone is a prescription drug approved for a different reason at a higher dose than the dose used in this study. However, “low dose naltrexone” is widely used, …
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