Found 16 dm-rheumatology trials
A listing of dm-rheumatology medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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The purpose of this study is to see how your body forms a protective response after vaccination and how it deals with viral variants. We are studying the immune responses to the COVID-19 vaccines.
The main purpose of this study is to understand how patients with giant cell arteritis (GCA) respond to an investigational drug called abatacept (also called Orencia). Abatacept is being tested to determine if it is effective in treating GCA. An investigational drug is one that is not approved by the …
The research study is being conducted to determine the utility of magnetic resonance imaging (MRI) in identifying inflammation of arteries supplying blood to the head, brain, and eyes, which may be useful in the diagnosis, prognosis, and treatment of giant cell arteritis (GCA; temporal arteritis). Study participants are eligible if …
This study investigates psoriatic arthritis (PsA) and spondyloarthritis (SpA).The study evaluates the safety and effectiveness of approved treatments for these conditions.Who can participate: Adults 18 years or older with joint conditions can join. Participants must not have other autoimmune inflammatory arthritis and should not be in a clinical trial for …
Systemic sclerosis is a rare chronic autoimmune connective tissue disease. B cells have been reported to play a central role in the pathogenesis of SSc and B cell depletion has been shown to offer benefit to patients with SSc. Belimumab is a monoclonal antibody, which inhibits the survival of B …
This is a platform study to assess the safety and efficacy of investigational products in participants with interstitial lung disease that is secondary to systemic sclerosis.
The purpose of this study is to see if the drugs methotrexate, azathioprine, adalimumab, infliximab, and tocilizumab are effective in treating relapsing polychondritis (RP). The study has 2 stages. Participants enrolled in the first stage of the study will receive methotrexate or azathioprine (if there is a medical contraindication to …
Systemic sclerosis (SSc) is a rare, chronic, autoimmune, connective tissue disease with one of the highest mortality rates among rheumatic diseases. Objective of the study is to evaluate the efficacy of efgartigimod for SC administration coformulated with rHuPH20 (efgartigimod PH20 SC) compared with placebo (placebo PH20 SC) on skin sclerosis …
The purpose of this study is to obtain long-term safety data and long-term maintenance of remission with avacopan treatment in subjects with ANCA associated vasculitis (AAV) on standard of care (SOC) background immunosuppressive therapy. Additionally, health-related quality of life measures and renal function will be assessed. Subjects with severe, active, …
This study investigates the impact of an investigational medication on psoriatic arthritis.The study evaluates the overall impact of the investigational medication on the symptoms and outcomes of psoriatic arthritis. It focuses on understanding how the medication affects the condition in general.Who can participate: Adults 18 years and older with a …
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