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Found 33 dm-gastroenterology trials

A listing of dm-gastroenterology medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

ALN-HSD-NASH-2130

99 or below
All genders
The goal of study 1 and study 2 is to evaluate the effects of ALN-HSD on liver fibrosis and other histologic features of NASH in participants with NASH and F2/F3 fibrosis and risk alleles for HSD17B13. Necessary screening procedures include blood tests, liver stiffness measurement, study-specific genotype criteria, and a …
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CROSSINGS

99 or below
All genders
The aim of this global Phase III study is to investigate the use of tezepelumab as a treatmentfor patients with EoE. This study will evaluate the efficacy and safety of tezepelumab 210 mgevery 4 weeks (Q4W) and tezepelumab 420 mg Q4W administered subcutaneously (SC) usingan accessorized pre-filled syringe (APFS) versus …
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Target-LD

99 or below
All genders
An Observational Study of Patients with Chronic Liver Disease
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Abbvie M21-446

99 or below
All genders
Study M21-446 is a Phase 2a, multicenter, open label proof of concept study to investigate the efficacy and safety of ABBV-668 in subjects with moderate to severe UC. The study contains a 30-day screening period, 16-week treatment period, and a 30-day follow up period from the last dose of study …
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Patent-E

99 or below
All genders
The primary objective of this study is to evaluate the safety and efficacy of the ProTractX3 DCB for the treatment of benign esophageal strictures. The ProTractX3 DCB is intended to treat benign strictures of the alimentary tract, combining mechanical dilation with localized delivery of the drug paclitaxel. The ProTractX3 DCB …
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Patent-B

99 or below
All genders
The primary objective is to determine the safety and efficacy of GIE Medicals ProTractX3 TTS DCB for the treatment of recurrent benign bowel strictures. The ProTractX3 DCB is intended to treat benign strictures of the alimentary tract, combining mechanical dilation with localized delivery of the drug paclitaxel. The goal of …
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ENGAGE

99 or below
All genders
This is a phase 2/3, multicenter, randomized, 3-part study investigating the efficacy, safety, tolerability, PK, and immunogenicity of dupilumab in adults and adolescents (12 years of age) with active EoG (with or without EoD).Eosinophilic gastritis (EoG) is a rare, chronic, allergic/immune mediated disease of the stomach, distinct from eosinophilic esophagitis …
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Sanofi

99 or below
All genders
The dupilumab clinical program in EoE has provided evidence that long-term suppression of IL-4 and IL-13 could lead to progressive improvement in fibrostenosis. . There is a need for longer term assessments with comprehensive functional, histological, molecular, clinical, and endoscopic assessments to characterize the risk of fibrotic progression as well …
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BDPI-20-004

99 or below
All genders
For a detailed list of objectives, please refer to Section 3, "Objectives" in the latest protocol. For a detailed list of primary outcomes, please refer to the Section 3.1, "Primary Endpoints" in the latest protocol. For detailed list of secondary outcomes, please refer to Section 3.2, " Secondary Endpoints" in …
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NN7730

99 or below
All genders
Effects of NNC0194-0499 alone and in combination with semaglutide, of semaglutide alone, and of cagrilintide alone and in combination with semaglutide on liver damage and alcohol use in people with alcohol-related liver disease
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