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Found 35 dm-gastroenterology trials

A listing of dm-gastroenterology medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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99 years or below
All genders
To evaluate the efficacy of icotrokinra versus placebo in inducing clinical response
99 years or below
All genders
The purpose of this study is to assess the efficacy and safety of RO7790121 (also known as afimkibart, formerly PF-06480605 and RVT-3101), referred to herein as afimkibart, in patients with moderately to severely active ulcerative colitis (UC). Afimkibart is a fully human immunoglobulin G1 (IgG1) monoclonal antibody (mAb) against tumor …
Healthy Volunteer Enteral Nutrition
18 years - 70 years
Accepts healthy volunteer
All genders
This is an Outpatient clinical trial of 20 healthy people assigned to drink nutritional shakes for either 60% of their calories or 100% of their calories for up to 4 days to understand changes in microbiome and metabolome resulting from consumption of the assigned diet.   Participants assigned to drink …
UPCC 04221 Collection of Samples from the United States Population for Optimization and Evaluation of Colorectal Cancer (CRC) Plasma Circulating Free-DNA (cfDNA) Marker Panel Performance (USOPTIVAL)
45 years - 84 years
Accepts healthy volunteer
All genders
This study investigates the use of circulating free-DNA (cfDNA) markers in blood to improve detection of colorectal cancer (CRC) and advanced adenomas. The purpose of this study is to collect blood samples and clinical data from participants in order to optimize a biomarker panel for better detection of these conditions.Participants …
Evaluating the Safety and Efficacy of Tradipitant vs. Placebo in Idiopathic and Diabetic Gastroparesis
18 years - 70 years
All genders
Phase 3
Interventional
To investigate the safety and efficacy of Tradipitant versus placebo in relieving nausea and other symptoms of gastroparesis.
18 years - 89 years
All genders
Interventional
This study investigates the best way to treat patients with Barrett's esophagus and low-grade dysplasia by comparing two procedures: endoscopic surveillance and endoscopic eradication therapy. Low-grade dysplasia is an early form of abnormal cell growth that may not always progress to cancer. Endoscopic surveillance involves using a camera-equipped tube to …
99 years or below
All genders
A Phase 2a, Randomized, Double-Blind, Placebo-Controlled, Multicenter, Dose-escalation, Proof-of-Concept Study Evaluating the Safety, Tolerability, Efficacy and Pharmacokinetics of INT-787 in Subjects with Severe Alcohol-Associated Hepatitis.
99 years or below
All genders
The purpose of the Pancreatic Cancer Early Detection (PRECEDE) Consortium is to conduct research on multiple aspects of early detection and prevention of pancreatic ductal adenocarcinoma (PDAC) by establishing a multi-site cohort of individuals with family history of PDAC and/or individuals carrying pathogenic/likely pathogenic germline variants (PGVs) in genes linked …
18 years - 99 years
All genders
Multi-center study to demonstrate impact of IBD learning health system approach that enables patients and care teams to deliver optimal health and high value care
99 years or below
All genders
I am requesting a reliance agreement with the external IRB Advarra. The purpse is to treat a single patient with gastroparesis who has requested expanded access with tradipitant.By doing so, we will also monitor the efficacy of tradipitant in reducing individual symptoms associated with gastroparesis in this single patient and …
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