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Found 7 diabetes-and-metabolism trials

A listing of diabetes-and-metabolism medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 RevitaT2Di Pivotal Study (REVITALIZE 1)
21 years - 70 years
All genders
The Revitalize-1 Study will look at a potential procedure called duodenal mucosal resurfacing (DMR). The DMR procedure acts on the first layer (mucosa) of the duodenum (the part of the small intestine located immediately after the stomach). By removing an excess layer, the treatment may improve blood sugar control. This …
 Emergence and Progression of Abnormal Glucose Tolerance in Cystic Fibrosis (Aim 1)
6 years - 50 years
All genders
The purpose of this research study is to test how high blood sugar develops and worsens over time in some people with cystic fibrosis.If you agree to take part, your participation can last for up to 7 years.As a participant in this research, all participants will:Complete overnight fastingComplete Mixed Meal …
99 years or below
All genders
To evaluate the safety and tolerability of CRN04894 Change from Baseline in morning (before 11:00 AM) serum A4 (androstenedione) at Week 12. Change from Baseline in morning (before 11:00) serum 17-OHP (17-hydroxyprogesterone) at Week 12.
 Investigation of the Effect of Branched Chain Amino Acids on Fat-Induced Insulin Resistance in Healthy Adults
18 years - 39 years
Accepts healthy volunteer
All genders
Phase 1
The study is designed to test the idea that branched chain amino acids, a specific component of all protein, and fat combine to cause a temporary state of insulin resistance. Insulin resistance is a condition that occurs when your body demands more insulin to control your blood sugar level. Branched chain amino …
 Effect of GLP-1 Agonist Therapy on Insulin Secretion in Adults with Pancreatic Insufficient Cystic Fibrosis and Abnormal Glucose Tolerance: a randomized  open-label  cross-over trial
18 years - 50 years
All genders
The research study is being conducted to better understand Cystic-Fibrosis Related Diabetes (CFRD) and to see the effects of an analog of the gut incretin hormone, GLP-1 (dulaglutide), has on individuals like with abnormal glucose tolerance. GLP-1 (dulaglutide) helps the pancreas release insulin, which controls blood sugar levels from getting …
 A Phase 1/2 Study to Evaluate the Safety, Tolerability, and Efficacy of VX-880 in Subjects Who Have Type 1 Diabetes Mellitus with Impaired Hypoglycemic Awareness and Severe Hypoglycemia
18 years - 65 years
All genders
Phase 1/2
Interventional
In T1D the body’s immune system destroys insulin producing cells called beta cells. This meansthe body cannot produce enough insulin to control the amount of sugar in the blood. Beta cellsare located in the pancreas and are part of clusters of cells called pancreatic islets.These cells produce hormones such as …
 TZIELD® (teplizumab-mzwv) in Patients with Stage 2 Type 1 Diabetes
8 years or above
All genders
Are you at risk for type 1 diabetes?Are you willing to receive a phone call every 6 months?For patients treated with TZIELD AND NOT treated with TZIELDYou may qualify to participate in an observational research studyAn observational study (you will not receive any experimental medication)Does not require on-site visitsParticipation will …