Found 64 abramson-cancer-center trials
A listing of abramson-cancer-center medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study investigates the effectiveness of a quantitative HER2 assay in distinguishing between patients with HER2 IHC1+ metastatic breast cancer who respond to treatment and those who do not. The purpose is to determine if this assay can reliably identify patients who are likely to benefit from receiving investigational medications …
This study investigates an imaging technique using an investigational medication and a special camera system to detect cancer in patients undergoing surgery for endometrial cancer. The purpose of this study is to assess how well the investigational medication works when used with this imaging technique during surgery.Participants will undergo several …
The purpose of this study is to investigate the cancer risks linked to CTNNA1 gene alterations. CTNNA1 gene changes, known as loss-of-function variants, may increase the risk for certain hereditary cancers such as gastric and breast cancer. This study will collect personal and family history from individuals with these gene …
This study investigates the use of an investigational medication, epcoritamab, before and after CAR-T cell therapy in patients with relapsed or refractory large B-cell lymphomas. This study aims to understand if epcoritamab can improve outcomes when used in conjunction with CAR-T cell therapy, a treatment where a patient's T cells …
This study investigates the occurrence of irregular heart rhythms in patients with chronic lymphocytic leukemia (CLL) who are treated with Bruton’s Tyrosine Kinase (BTK) inhibitors. The purpose of this study is to use wearable technology to monitor heart rhythms and blood pressure at home, aiming to understand how often patients …
This study investigates the effectiveness of personalized mapping techniques for patients with Glioblastoma, a type of brain cancer. The purpose of this study is to compare two different mapping methods used in tumor treating fields (TTFields) therapy, which is a type of electrical therapy that has shown to improve survival …
This study investigates the use of polygenic risk scores (PRS) and novel early detection strategies in women at risk for ovarian cancer. The purpose of this study is to understand how women incorporate these tools in their decisions about cancer screening and risk-reducing surgery. Researchers will conduct qualitative interviews with …
This study investigates the treatment of non-muscle invasive bladder cancer. The purpose of this study is to explore the barriers and facilitators affecting treatment compliance and to test a Bacillus Calmette-Guerin (BCG) at-home program. Participants will be divided into two study arms: one focusing on understanding treatment compliance and the …
This study investigates the safety and effectiveness of adding RP2, an investigational treatment, to the standard chemotherapy regimen, FLOT, for patients with stage II or higher, non-metastatic gastroesophageal adenocarcinoma. The purpose of this study is to determine if injecting RP2 directly into the tumors of the stomach and esophagus, combined …
This study investigates how cancer treatment with immune checkpoint inhibitors (ICI) can lead to the development of autoimmunity. The purpose is to understand the genetic and immune system characteristics that cause some cancer patients to experience immune-related adverse events (irAE) after receiving checkpoint inhibitor therapy.Participants will provide peripheral blood and …
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