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Found 9 ps-affective-disorders-program trials

A listing of ps-affective-disorders-program medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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65 years or below
All genders
This is an international, multicenter, randomized, double-blind, placebo-controlled, parallel-group, fixed-dose study in patients with a primary diagnosis of MDD to evaluate the efficacy of lumateperone 42 mg administered once daily compared with placebo as adjunctive treatment to antidepressant therapy
74 years or below
All genders
The study will investigate 20 mg seltorexant as adjunctive treatment to SSRI/SNRI antidepressants for major depressive disorder (MDD) compared with placebo as adjunctive therapy in patients with a partial response to first line antidepressant therapy.
25 years - 65 years
All genders
Interventional
The purpose of this study is to investigate Major Depressive Disorder. This study investigates how ketamine affects the brain by looking at changes in a chemical called glutamate.The study evaluates the effects of ketamine on mood and brain activity. Researchers will use a special imaging technique to see how ketamine …
99 years or below
All genders
This is a randomized, double-blind, multicenter, placebo-controlled study to evaluate the efficacy in delaying relapse of depressive symptoms as well as the safety and tolerability of NBI-1065845 1 mg administered orally once daily (qd) as an adjunctive antidepressant in subjects 18 years of age with moderate or severe MDD, who …
99 years or below
All genders
To determine the efficacy of VLS-01-BU compared with placebo in improving depressive symptoms in participants with TRD 4 weeks after initiating treatment
Sleep Slow-Wave Activity as a Potential Vulnerability and Modifiable Risk Factor in Older Black Adults: Examining the Relationship from  Chronic Stress to Accelerated Aging and Alzheimer’s Disease
55 years - 80 years
All genders
This research study is looking to identify a modifiable sleep disparity, slow-wave activity dysfunction, as a potential mechanism that accelerates the process of aging and contributes to the development of Alzheimer’s disease in older Black adults.
99 years or below
All genders
This is a randomized, double-blind, placebo-controlled study evaluating the safety and efficacy of a single dose of RE104 (30 mg) versus placebo for the treatment of GAD.
18 years or above
All genders
Interventional
This study investigates the impact of different outreach strategies on a telehealth-delivered collaborative care program for patients with lung cancer. The purpose is to compare two approaches: a more intensive 'high touch' strategy versus a standard outreach. The study focuses on patients who are experiencing depression and/or anxiety, which are …
18 years - 80 years
All genders
Phase 2
Interventional
This study investigates the use of an investigational medication to treat Adjustment Disorder (AjD) in patients with cancer and other medical conditions such as Amyotrophic Lateral Sclerosis (ALS), Multiple Sclerosis (MS), Parkinson's Disease (PD), or Idiopathic Pulmonary Fibrosis (IPF). The purpose of this study is to assess whether a single …