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Found 14 op-ophthalmology trials
A listing of op-ophthalmology medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study investigates the safety and initial effects of a gene therapy for patients with a type of inherited eye disease called LCA5-associated inherited retinal degeneration (LCA5-IRD). The purpose is to understand how this condition progresses over time and to see how patients respond to different doses of an investigational …
Patients with an epiretinal membrane (ERM) are either referred for vitrectomy, or if their vision is normal are deferred until vision declines. It is unknown if delaying surgery results in worse visual acuity than if surgery is performed earlier. Additionally, a common symptom from an ERM is metamorphopsia. The objective …
This study investigates X-linked retinoschisis (XLRS).The purpose of this study is to evaluate the safety and effectiveness of an investigational medication.Who can participate: Participants must be 6 years or older and have a clinical diagnosis of XLRS due to RS1 mutations. Both males and females with specific genetic criteria can …
This study investigates the effectiveness of Selective Laser Trabeculoplasty (SLT) at low energy levels for individuals with ocular hypertension and glaucoma. The purpose of this study is to compare the outcomes of low-energy SLT with standard-energy SLT in maintaining eye health.The study focuses on assessing whether repeating low-energy SLT annually …
This study investigates retinal dystrophy. The purpose of this study is to gather information about genetic variants associated with this condition.The study evaluates the natural history and structural-functional relationships of genetic variants in retinal dystrophy. It also looks into risk factors for progression and investigates subpopulations for future clinical trials.Who …
The purpose of this study is to (1) determine if circulating metabolites, including sphingolipids, are associated with severity of diabetic retinopathy (DR) in participants with diabetes mellitus type 2 and to (2) identify metabolic risk and protective factors that are associated with the development and progression of DR.
The purpose of this study is to investigate acanthamoeba keratitis. It evaluates whether including topical corticosteroids can improve vision in patients with this condition.This study focuses on evaluating the effectiveness of topical corticosteroids in treating acanthamoeba keratitis. It looks at how these medications might affect vision improvement.Who can participate: Participants …
This is an intermediate-size patient population expanded access application of 0.06% BRM421 Ophthalmic Solution for the treatment of Limbal Stem Cell Deficiency. no primary outcomes - intermediate-size patient population expanded access protocol no secondary outcomes - intermediate-size patient population expanded access protocol
This study aims to compare the safety and efficacy of RGN-259 to placebo for the treatment of Neurotrophic Keratopathy (NK)
This is a Phase 3 study to evaluate the efficacy and safety of intranasal cengermin compared with vehicle control in adult participants recently diagnosed with or suspected Non-Arteritic Ischemic Optic Neuropathy (NAION)
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