Found 9 pulmonary-medicine trials
A listing of pulmonary-medicine medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
ASPEN- A Phase 3 Randomized Double-Blind Placebo-Controlled Study to Assess the Efficacy Safety and Tolerability of Brensocatib Administered Once Daily for 52 Weeks in Subjects With Non-Cystic Fibrosis Bronchiectasis
Phase 3
Penn Medicine patients already participating in protocol INS1007 301 will be invited to participate in this study. The Pharmacokinetic (PK) portion of this substudy is designed to evaluate the amount of brensocatib present in your blood at certain time periods before and after the study drug is administered, and the …
Cooling to Help Injured lungs (CHILL) for Therapeutic Hypothermia in Patients with ARDS (acute respiratory distress syndrome )
Phase 2
This study will analyze the potential lung protective effect of mild therapeutic hypothermia (TH), similar to that used for cardiac arrest, in ICU patients with acute respiratory distress syndrome (ARDS).
A Randomized Study to Compare Efficacy Safety and Tolerability of Macitentan 75mg Versus Macitentan 10mg in Patients with Pulmonary Arterial Hypertension Followed by an Open-label Treatment Period with Macitentan 75mg
Phase 3
TThe research study is being conducted to compare macitentan 75 mg with the approved macitentan 10 mg to see if it is well tolerated, safe and useful for treating patients with pulmonary arterial hypertension (PAH).
PEERLESS Study
The FlowTriever Retrieval/Aspiration System (referred to as “FlowTriever”) is an FDA-cleared device designed to treat pulmonary embolism (PE). A PE is a blood clot trapped in your lung. The FlowTriever is used to remove the clot by pulling it into a catheter so that the clot can be removed from …
Effect of study drug IL-4RR576 polymorphism on response to dupilumab in asthma
Phase 4
The purpose of this study is to learn if the study drug (Dupixent® Dupilumab) helps to control asthma. We are particularly interested in understanding if people who have a certain genetic make-up (genotype) will respond better to this treatment. Participants will take inhaler (Dulera®mometasone/formoterol) about 2-12 weeks. Total study duration …
Assessment of Chronic Lung Allograft Dysfunction Using Single-Breath & Multi-Breath Hyperpolarized Xenon 129 MRI
The research study is being conducted to determine the effectiveness of using hyperpolarized xenon-129 (HP 129-Xe) magnetic resonance imaging (MRI) in diagnosing and predicting the clinical course of patients who received lung transplantation.
Functional and Structural Assessment of Endobronchial Valve Recipients Using Dynamic Hyperpolarized Xenon-129 MRI
The research study is being conducted to determine the effectiveness of using hyperpolarized xenon-129 magnetic resonance imaging (MRI) in diagnosing and predicting treatment outcomes for patients who received endobronchial valve (EBV) therapy to treat chronic obstructive pulmonary disease (COPD). COPD is a disease of the lungs caused most often by …
A Clinical Study of Aliya Pulsed Electric Fields (PEF) Delivered Prior to Standard of Care Treatment of Advanced Cancer
Phase 4
The Investigation Device Exemption (IDE) study will evaluate the safety of delivering Aliya PEF in patients with metastatic cancer within the lungs or stage IV non-small cell lung cancer NSCLC) who are treatment-naïve and indicated for first-line standard of care (SOC) cancer therapy.
Visceral adipose tissue and frailty in idiopathic pulmonary fibrosis
The research study is being conducted to better understand how fat and muscle are related to disability and health-related quality of life in people with idiopathic pulmonary fibrosis.
