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Found 19 metabolism trials

A listing of metabolism medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 Dynamic Nuclear Polarization-MR Spectroscopic Imaging of Hepatocellular Carcinoma Metabolism to Predict Response Following Locoregional or Systemic Therapy

Dynamic Nuclear Polarization-MR Spectroscopic Imaging of Hepatocellular Carcinoma Metabolism to Predict Response Following Locoregional or Systemic Therapy

18-99 years
All genders
Phase 2
Interventional
The research study is being conducted to evaluate a new imaging technique for detecting the response of hepatocellular carcinoma (HCC) to locoregional or systemic therapy. Locoregional therapies or LRT are called Transarterial Chemoembolization or TACE, Transarterial Radioembolization or TARE and Microwave Ablation or MWA. Systemic therapies or ST are therapy …
 RevitaT2Di Pivotal Study (REVITALIZE 1)

RevitaT2Di Pivotal Study (REVITALIZE 1)

21-70 years
All genders
The Revitalize-1 Study will look at a potential procedure called duodenal mucosal resurfacing (DMR). The DMR procedure acts on the first layer (mucosa) of the duodenum (the part of the small intestine located immediately after the stomach). By removing an excess layer, the treatment may improve blood sugar control. This …

In vivo Mapping of Muscle Specific Metabolism

18-40 years
All genders
Adult healthy volunteers in the age group of 18-40 years, both male and female, and willing to participate in MRI at the University of Pennsylvania, department of  radiology facilitiesMild exercise  with calf muscle  briefly  is required, and MRI will be performed before and after exercise.
 Metabolomic Reprogramming in insomnia as a Function of Objective Sleep Duration

Metabolomic Reprogramming in insomnia as a Function of Objective Sleep Duration

25-50 years
All genders
The research study is being conducted to understand how insomnia and the amount of sleep people get at night affect metabolism. Four groups of people will be asked to participate: individuals with insomnia who sleep >6 hours per night, individuals with insomnia who sleep <6 hours per night, individuals without …

Effects of Nutritional Ketosis on Alcohol Metabolism

21-50 years
Healthy Volunteer
All genders
The research study is being conducted to better understand the effects of ketosis on brain functioning after three separate 3-day dietary interventions and the acute effects of alcohol during three separate MRI and lab visits after consuming about 4-5 alcohol beverages.
 Mapping Muscle Specific Metabolism in Different Age Groups

Mapping Muscle Specific Metabolism in Different Age Groups

18-80 years
Healthy Volunteer
All genders
The purpose of the study is to determine the changes in muscle metabolites by MRI before and after exercise.    The MRI will be performed while performing mild exercise of the calf muscle for 1-3 minutes.  We are actively recruiting adults between 18-30, 45-55 and 70-80.  Volunteers will be non-diabetic, …

Monitoring brain metabolism after glucose intake by MRI methods

99 years and younger
All genders
Glucose is a major energy source for brain cells. Changes in blood glucose also leads to changes in supply or availability of glucose to brain cells. Changes in various brain metabolites when mapped in different areas of the brain will allow, an understanding of the effects of such changes in …
 A Randomized Trial Evaluating the Efficacy and Safety of Control-IQ Technology in Adults with Type 2 Diabetes Using Basal-Bolus Insulin Therapy (2IQP)

A Randomized Trial Evaluating the Efficacy and Safety of Control-IQ Technology in Adults with Type 2 Diabetes Using Basal-Bolus Insulin Therapy (2IQP)

18-99 years
All genders
If you have type 2 diabetes and use short and long acting insulin then we would love to talk to you!   The study is being done to learn if an automated insulin delivery (AID) system can safely control blood sugar in people with type 2 diabetes. We will refer …

Obicetrapib on Lipoprotein Metabolism

99 years and younger
All genders
Please see section 2 of the protocol, "Study Objectives and Hypotheses" Please see section 2 of the protocol, "Study Objectives and Hypotheses" Please see section 2 of the protocol, "Study Objectives and Hypotheses"
 Brain Arterio-Venous Metabolomic Profiling

Brain Arterio-Venous Metabolomic Profiling

18-99 years
All genders
The research study is being conducted to better understand brain metabolism, i.e. how the brain uses and consumes the various nutrients that are available in the blood. Changes in brain metabolism have been implicated in dementia and psychiatric disorders, as well as short- and long-term outcomes of traumatic brain injury …
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