Found 25 infectious-diseases trials
A listing of infectious-diseases medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Direct Lysis of Staph Aureus Resistant Pathogen Trial of Exebacase (DISRUPT)
Phase 3
The purpose of this superiority study is to evaluate the efficacy and safety of exebacase in addition to standard of care antibiotics (SoCA) compared with SoCA alone for the treatment of patients with Staphylococcus aureus (S. aureus) bloodstream infections (BSI), including right-sided infective endocarditis (IE). Patients will be randomized to …
Study to Evaluate the Safety and Efficacy of GS-5423 and GS-2872 in Combination With Lenacapavir (GS-6207) in Virologically Suppressed Adults With HIV-1 Infection
Phase 1
The primary objective of this study is to evaluate the safety and tolerability of a combination of the broadly neutralizing antibodies (bNAbs) GS-5423 and GS-2872 in combination with the HIV capsid inhibitor lenacapavir (LEN).
Investigational COVID-19 Vaccine Trial
Phase 1
This clinical research trial is being conducted to find out whether the administration of two investigational dMab products (not approved by the US FDA) with an investigational device is safe, tolerated, and can produce enough antibodies in your blood that may indicate the ability to prevent infection of COVID-19.
Antiviral medication to reduce symptoms of COVID-19: A phase 3, placebo-controlled trial
Phase 3
If you tested positive for COVID-19 within the last 5 days, you may be eligible to participate in a research study to test the ability of a pill to reduce COVID-19 symptoms.
Long Acting Therapy to Improve Treatment SUccess in Daily LifE (The LATITUDE Study)
Phase 3
This study is meant for patients who have difficulty taking their HIV meds as prescribed. One goal of the study is to test the effectiveness of long-acting antiretroviral therapy (ART) -- a once-a-month injection that replaces daily ART pills. You will also receive compensation for participating in this study, with …
Potential Role of FDG-PET-CT in Assessing Cardio-Vascular-Pulmonary CNS and Other Complications of COVID-19 Infection
The research study is being conducted to assess the role of Fluorodeoxyglucose (FDG)-Positron Emission Tomography (PET) imaging (a radiology scan) for monitoring the course of COVID-19 infection.
A5128: Plan for Obtaining Informed Consent to Use Stored Human Biological Materials (HBM) for Currently Unspecified Analyses
Some samples (for example, blood, tissue, fluids) taken from you during this or another research study might be useful for research at some later date. This study is being done so that your samples can be stored and used at some later date for research studies, including genetic testing. These …
SCY-078-302
PRIMARY OBJECTIVE: To demonstrate that treatment of Invasive Candidiasis/ Candidemia with IV echinocandin followed by oral ibrexafungerp is non-inferior to IV echinocandin followed by oral fluconazole based on 30-day all-cause mortality (ACM). SECONDARY OBJECTIVES: To demonstrate that treatment of Invasive Candidiasis/ Candidemia with intravenous (IV) echinocandin followed by oral ibrexafungerp …
HPTN 102/PURPOSE 3
Phase 2
This is a Phase 2, open-label, multicenter, randomized study to evaluate the PK, safety, and acceptability of LEN subcutaneous (SC) injection compared with oral F/TDF in cisgender women who would benefit from PrEP. This study has 2 parts. Randomized Phase: ppts will be randomized in a 1:1 ratio to receive …
HVTN 313: A Phase 1 research study to test an experimental vaccine against HIV
The primary hypotheses are that the vaccine regimens will be safe and well tolerated and the prime-boost vaccine regimens that include Ad4-Env145NFL and Trimer 4571 as heterologous boosts will contribute to the development of B-cell and antibody (Ab) responses directed to the cross-conserved CD4 binding site (CD4bs) and gp120/gp41 fusion …
