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Found 12 pe-pediatrics trials

A listing of pe-pediatrics medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 Pharmacogenetics and Variability In Drug Exposure and Clinical Response to Corticosteroids in Severe BPD
1 years and younger
All genders
Observational
This observational study will follow infants born with a gestational age of less than 32 weeks requiring positive pressure ventilation and planned clinical treatment with corticosteroids for bronchopulmonary dysplasia.
 The Whole Health Study: Collaborative Care for OUD and Mental Health Conditions: Randomized Trial
18-99 years
All genders
We are interested in comparing 3 care conditions to determine which condition is best to help people with opioid use disorder (OUD) and mental illness reduce their drug use and improve their psychiatric symptoms. The model we are testing is called collaborative care. This model uses a team-based approach in …
 The NICU Antibiotics and Outcomes Trial (NANO)
99 years and younger
All genders
The goal of the NANO trial is to study the longstanding clinical practice of empirically administering intravenous antibiotics to extremely low birthweight (ELBW) infants in the first days of life. In this 802-subject multicenter placebo-controlled randomized clinical trial, the hypothesis to be tested is that the incidence of adverse outcomes …
 The Diaphragmatic Initiated Ventilatory Assist (Diva) Trial
99 years and younger
All genders
Interventional
DIVA is a pragmatic randomized clinical trial (RCT) to determine: among (P) preterm infants born 24-27 6/7 weeks gestation undergoing extubation from mechanical ventilation, whether (I) Non-invasive neurally adjusted ventilatory assist (NIV-NAVA) (C) compared with Non-synchronized nasal intermittent positive pressure ventilation (NS-NIPPV), will reduce the incidence of (O) extubation failure …
25-65 years
All genders
Interventional
This is a study that evaluates SAGE-718 in participants with Huntington's Disease.
99 years and younger
All genders
To compare dependent lung ventilation (as assessed with EIT, vertical center of ventilation (CoV(v)) measure) between extremely preterm infants treated with NIV-NAVA and those treated with NS-NIPPV. To compare global ventilation homogeneity (as assessed with EIT, global inhomogeneity index (GI) measure) between extremely preterm infants treated with NIV-NAVA to those …
18-45 years
All genders
Join the largest, long-term nationwide study that hopes to better understand baby brain development. Leading researchers in the fields of child development and neuroscience will work with participating families and their children to understand how the brain develops and is affected by exposure to substances and other environmental, social, and …
 A Trial of Endocrine Response in Women with Invasive Lobular Breast Cancer
18-99 years
All genders
Phase 2
To study whether fulvestrant is more effective than anastrozole or tamoxifen in reducing Ki67 in ILC and whether that Ki67 reduction will correlate with alterations in expression of ER and ER-regulated genes. Differential Ki67 effect in this study will serve as a surrogate for outcome of ILC patients on endocrine …
 Cystic Fibrosis Microbiome
18-99 years
All genders
Among lung transplant recipients who survive to 5 years, half suffer from chronic lung allograft dysfunction (CLAD). This study will evaluate how changes in the lung microbiome may cause CLAD in Cystic Fibrosis patients who have been transplanted. This is a case-control study of Cystic Fibrosis lung transplant recipients to …
 Myeloid derived suppressor cell expression in newborn infants: an observational cohort study
1-1 years
All genders
This research study is being conducted to study a type of white blood cells called MDSC in newborn babies. These cells help regulate our body’s immune system. Learning more about these cells may help us to better understand immune function in newborn babies.
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