A listing of ro-radiation-oncology medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
This research study is being done to study the safety and toxicity of proton whole pelvis radiation, a type of external beam radiation treatment, for gynecologic cancers after surgery. Currently, for such gynecology cancers, Image- guided Intensity Modulated Radiation Therapy (IG-IMRT) is being done after hysterectomy as the standard treatment. …
To evaluate safety of ultrahypofractionated proton therapy to the prostate and whole pelvis with HDR brachytherapy boost. The technique will be deemed safe if 10% of patients experience a CTCAE grade 3 or higher genitourinary or gastrointestinal toxicity cumulatively over the first year of treatment.To evaluate for multiple domains of …
This study plans to treat subjects with pembrolizumab by infusion in combination with radiation therapy to see if the combination is an effective treatment for relapsed/refractory non-Hodgkin lymphoma. Radiation therapy is commonly used to treat relapsed/refractory non-Hodgkin lymphoma. Although pembrolizumab is FDA-approved for some cancers, including Hodgkin lymphoma, it is …
Subjects will be recruited from the Radiation Oncology and Neurosurgery practices at the Hospital of the University of Pennsylvania. The treating radiation oncologist will determine if the patient is a potential research candidate and has the capacity to consent. The goal of this study is to collect and analyze blood …
Primary Objectives Evaluate utility of FES PET/CT to detect estrogen receptor (ER+) uterine cancer lesions in patients with recurrent or metastatic uterine cancer Secondary Objectives Evaluate utility of FES PET/CT compared to standard axial cross-sectional imaging and/or FDG PET/CT when available to establish tumor heterogeneity and staging Correlate FES uptake …
To determine if overall survival (OS) is improved with proton beam therapy (PBT) treatment as compared to intensity modulated radiation therapy (IMRT) as part of planned protocol treatment for patients with esophageal cancer. To determine if OS with PBT is non-inferior to IMRT as part of planned protocol treatment and …
Please see section 3 of the protocol for objectives and endpoints Please see section 3 of the protocol for objectives and endpoints Please see section 3 of the protocol for objectives and endpoints
The primary objective of this Phase I study is to establish the safety of adjuvant concurrent radiation therapy and immunotherapy. Safety will be based on acute grade 3 or higher pelvic radiation related toxicity. Secondary objectives are to estimate late toxicities, quality of life, locoregional and distant failure and overall …
The principal hypothesis of the Varian CRA randomized trial is that Varian CRA is safer and provides at least equivalent efficacy compared to repeat CA for patients with high-risk refractory VT who have experienced VT recurrence after CA and are candidates for additional CA.
To determine whether or not the 6D target is 0.5mm and 0.5deg for greater than 95% of treatment time using a robotic head holder. The primary study endpoint of the study is as follows: success will be defined as to whether or not the 6D intracranial target is 0.5mm and …